Evidence map›Paper›PMID 20351215›Full record

ArticleJournal of clinical microbiology2010

New automated hepatitis C virus (HCV) core antigen assay as an alternative to real-time PCR for HCV RNA quantification.

Yongjung Park, Jong-Han Lee, Beom Seok Kim, Do Young Kim, Kwang-Hyub Han, Hyon-Suk Kim

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
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  8. Hepatitis C core antigen highly correlated to HCV RNA.The Kaohsiung journal of medical sciences · 2018
    Article
  9. Review
  10. Article
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  12. Update on hepatitis B and C virus diagnosis.World journal of virology · 2015
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yongjung ParkDepartment of Laboratory Medicine, Yonsei University College of Medicine, 250 Seongsan-no, Seodaemun-gu, Seoul 120-752, South Korea.
Jong-Han Lee
Beom Seok Kim
Do Young Kim
Kwang-Hyub Han
Hyon-Suk Kim

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An automated hepatitis C virus (HCV) antigen (Ag) assay was evaluated with clinical samples. Determination of HCV Ag and RNA levels in 282 subjects using Abbott HCV Ag and Roche Cobas TaqMan assays revealed that these two tests were highly correlated (r = 0.9464). Thus, the HCV Ag assay could be an alternative test to quantitative reverse transcription-PCR.

Indexed as

Antigens, ViralAutomationHepacivirusHumansReverse Transcriptase Polymerase Chain ReactionRNA, ViralStatistics as TopicViral Core ProteinsViral LoadAntigens, Viralnucleocapsid protein, Hepatitis C virusRNA, ViralViral Core Proteins

Identifiers

PMID20351215
PMCPMC2884480

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.