Evidence map›Paper›PMID 20350944›Full record

ArticleAntimicrobial agents and chemotherapy2010

Madurella mycetomatis is not susceptible to the echinocandin class of antifungal agents.

Wendy W J van de Sande, Ahmed H Fahal, Irma A J M Bakker-Woudenberg, Alex van Belkum

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Review
  5. Article
  6. In vitro susceptibility testing for black grain eumycetoma causative agents.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2021
    Article
  7. Development and Validation of anAntimicrobial agents and chemotherapy · 2021
    Article
  8. Diagnostic implications of mycetoma derived from Madurella pseudomycetomatis isolates from Mexico.Journal of the European Academy of Dermatology and Venereology : JEADV · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Mycetoma medical therapy.PLoS neglected tropical diseases · 2014
    Review
  15. Review
  16. Subcutaneous fungal infections.Current infectious disease reports · 2012
    Article
  17. Article
  18. Article
  19. Mycetoma: An Update.Indian journal of dermatology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Wendy W J van de SandeErasmus MC, University Medical Center Rotterdam, Department of Medical Microbiology and Infectious Diseases' CE Rotterdam, The Netherlands. w.vandesande@erasmusmc.nl
Ahmed H Fahal
Irma A J M Bakker-Woudenberg
Alex van Belkum
Erasmus MC · NLErasmus University Rotterdam · NLUniversity of Khartoum · SD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eumycetoma caused by Madurella mycetomatis is treated surgically and with high doses of ketoconazole. Therapeutic responses are poor, and recurrent infections are common. In search of therapeutic alternatives in the treatment of mycetoma, we determined the in vitro susceptibilities of M. mycetomatis isolates against caspofungin, anidulafungin, and micafungin. As a comparator fungus, Aspergillus fumigatus was used. Minimal effective concentrations (MECs) and MICs were assessed and compared to those of ketoconazole. M. mycetomatis isolates were not susceptible to the echinocandins.

Indexed as

AnidulafunginAntifungal AgentsAspergillus fumigatusCaspofunginDrug Resistance, FungalEchinocandinsHumansIn Vitro TechniquesLipopeptidesMadurellaMicafunginMicrobial Sensitivity TestsMycetomaAnidulafunginAntifungal AgentsCaspofunginEchinocandinsLipopeptidesMicafungin

Identifiers

PMID20350944
PMCPMC2876377
OpenAlexW2145876175

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.