Evidence map›Paper›PMID 20350374›Full record

ArticleEmerging infectious diseases2010

Phylogenetic analysis of enterohemorrhagic Escherichia coli O157, Germany, 1987-2008.

Christian Jenke, Dag Harmsen, Thomas Weniger, Jorg Rothganger, Eija Hyytia-Trees, Martina Bielaszewska, Helge Karch, Alexander Mellmann

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christian JenkeInstitute for Hygiene, Munster, Germany.
Dag Harmsen
Thomas Weniger
Jorg Rothganger
Eija Hyytia-Trees
Martina Bielaszewska
Helge Karch
Alexander Mellmann

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multilocus variable number tandem repeat analysis (MLVA) is a subtyping technique for characterizing human pathogenic bacteria such as enterohemorrhagic Escherichia coli (EHEC) O157. We determined the phylogeny of 202 epidemiologically unrelated EHEC O157:H7/H- clinical isolates through 8 MLVA loci obtained in Germany during 1987-2008. Biodiversity in the loci ranged from 0.66 to 0.90. Four of 8 loci showed null alleles and a frequency < or =44.1%. These loci were distributed among 48.5% of all strains. Overall, 141 MLVA profiles were identified. Phylogenetic analysis assigned 67.3% of the strains to 19 MLVA clusters. Specific MLVA profiles with an evolutionary persistence were identified, particularly within sorbitol-fermenting EHEC O157:H-.These pathogens belonged to the same MLVA cluster. Our findings indicate successful persistence of this clone.

Indexed as

Escherichia coli InfectionsEscherichia coli O157Genes, BacterialGenetic VariationGermanyHumansMinisatellite RepeatsPhylogenyPolymerase Chain Reaction

Identifiers

PMID20350374
PMCPMC3321953

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.