ArticleInternational journal of legal medicine2010
Trends in methadone-related deaths in Zurich.
Article in International journal of legal medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Characterizing post-mortem blood concentrations in methadone-related deaths.International journal of legal medicine · 2026Pooled it
- Randomized controlled trial of a computerized opioid overdose education intervention.Drug and alcohol dependence · 2017Trial
- Correlates of cocaine use during methadone treatment: implications for screening and clinical management (ANRS Methaville study).Harm reduction journal · 2016Trial
- Analysis of postmortem dermal extracts is an efficient illicit drug screening method supporting forensic medicine.Scientific reports · 2026Article
- The Role of Risk or Contributory Death Factors in Methadone-Related Fatalities: A Review and Pooled Analysis.Metabolites · 2021Article
- Brain/blood ratios of methadone and ABCB1 polymorphisms in methadone-related deaths.International journal of legal medicine · 2021Article
- Investigating opioid-related fatalities in southern Sweden: contact with care-providing authorities and comparison of substances.Harm reduction journal · 2020Article
- Opioid Overdose History, Risk Behaviors, and Knowledge in Patients Taking Prescribed Opioids for Chronic Pain.Pain medicine (Malden, Mass.) · 2017Article
- Opioid Overdose Experience, Risk Behaviors, and Knowledge in Drug Users from a Rural versus an Urban Setting.Journal of substance abuse treatment · 2016Article
- Intravenous methadone application as a serious risk factor for an overdose death: methadone-related fatalities in Hamburg from 2007 to 2012.International journal of legal medicine · 2014Article
- Prognostic factors in acute methadone toxicity: a 5-year study.Journal of toxicology · 2014Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Methadone has a long and successful history in the treatment of opioid addiction. In recent years, it has become popular again--as potent and inexpensive analgesic in patients with chronic pain. Since methadone has been used fatalities have been reported. In our study all methadone-associated deaths in Zurich from 1998 to 2007 were analysed. Most of the 146 detected deaths of the past 10 years occurred during substitution programmes or illicit intake of methadone while only three of them could be attributed to methadone used as an analgesic. Noticeable in our study was the high percentage of cases of combined drug intoxication (76%). The most frequent co-intoxicants were alcohol and cocaine. Mortalities attributed to methadone intoxication alone were a rare finding and could only be detected in five cases of deceased who had received methadone maintenance treatment. The aim of our study is to assess the trends in the number and nature of methadone-related fatalities in Zurich during the last 19 years. For this purpose a previous study from Zurich (1989-1997) was included, whereby a very long observation period and large number of cases resulted.
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Registered trials
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