ArticleMolecular biology reports2011
Single nucleotide polymorphisms of the prolactin receptor (PRLR) gene and its association with growth traits in Chinese cattle.
Article in Molecular biology reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 35 citations in OpenAlex.
- Genes and Gene Functions Associated with Morphological, Productive, Reproductive, and Carcass Quality Traits in Pigs: A Functional Bioinformatics Approach.Current issues in molecular biology · 2026Article
- Association of GenesInternational journal of molecular sciences · 2025Article
- Association analysis of single-nucleotide polymorphism in prolactin and its receptor with productive and body conformation traits in Liaoning cashmere goats.Archives animal breeding · 2022Article
- Goat Genomic Resources: The Search for Genes Associated with Its Economic Traits.International journal of genomics · 2020Review
- Molecular characterization and an 80-bp indel polymorphism within the prolactin receptor (3 Biotech · 2019Article
- Go with the flow-biology and genetics of the lactation cycle.Frontiers in genetics · 2015Review
- Genetic analysis of prolactin gene in Pakistani cattle.Molecular biology reports · 2013Article
- Bivariate genome-wide association analysis of the growth and intake components of feed efficiency.PloS one · 2013Article
- Mutations in the exon 10 of prolactin receptor gene change the egg production performance in Wanjiang white goose.Molecular biology reports · 2012Article
- Application of alternative models to identify QTL for growth traits in an F2 Duroc x Pietrain pig resource population.BMC genetics · 2010Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetic polymorphism of the prolactin receptor (PRLR) gene was detected by PCR-SSCP and DNA sequencing methods in 665 individuals from five Chinese cattle breeds. The results showed that at the P1 locus, three observed genotypes (AA, AB and BB), two linked SNPs (G1267A and T1268C), and one missense mutation (S18N) within a putative signal peptide were determined. The frequencies of haplotypes A and B in the five breeds were 0.596-0.802 and 0.198-0.404, respectively. Polymorphism of the PRLR gene was shown to be significantly associated with growth traits in the Nanyang breed. Individuals with genotype BB had greater hucklebone width, body weight and average daily gain than those with genotype AA at 6 months old (P<0.01), as well as better body height, body length and heart girth when 6 months (P<0.05). This study revealed for the first time that the PRLR gene is a promising candidate gene that affects growth traits in cattle.
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