Evidence map›Paper›PMID 20347418›Full record

ArticleMolecular cell2010

Stabilizing and remodeling the blocked DNA replication fork: anchoring FANCM and the Fanconi anemia damage response.

Larry H Thompson, Nigel J Jones

Abstract readComment
PubMed Publisher
In one paragraph

Article in Molecular cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Larry H ThompsonBiology and Biotechnology Division, L452, Lawrence Livermore National Laboratory, P.O. Box 808, Livermore, CA 94551-0808, USA. thompson14@llnl.gov
Nigel J Jones

Funding

Homologous Recombination & Human Cell RadiosensitivityR01CA112566 · NCI · UNIVERSITY OF CALIF-LAWRNC LVRMR NAT LAB · PI THOMPSON, LAWRENCE H · 2006 to 2009
$1.4M
NCI NIH HHS CA112566
6 · The paper itself

Abstract

In this issue of Molecular Cell, Yan et al. (2010) and Singh et al. (2010) identify an evolutionarily conserved FANCM-associated histone-fold MHF heterodimer (MHF1-MHF2) that promotes the remodeling of artificial replication forks and confers cellular resistance to DNA crosslinks and camptothecin.

Indexed as

Chromatin Assembly and DisassemblyDNA ReplicationGenomic InstabilityDNA HelicasesEvolution, MolecularFanconi AnemiaHumansProtein MultimerizationSignal TransductionDNA HelicasesFANCM protein, human

Identifiers

PMID20347418

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.