Evidence map›Paper›PMID 20346133›Full record

Trial reportBMC musculoskeletal disorders2010

The cost-effectiveness of a treatment-based classification system for low back pain: design of a randomised controlled trial and economic evaluation.

Adri T Apeldoorn, Raymond W Ostelo, Hans van Helvoirt, Julie M Fritz, Henrika C W de Vet, Maurits W van Tulder

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC musculoskeletal disorders, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Models of care for managing non-specific low back pain.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. The McKenzie method for (sub)acute non-specific low back pain.The Cochrane database of systematic reviews · 2023
    Pooled it
  3. Pooled it
  4. Cost-effectiveness of a classification-based system for sub-acute and chronic low back pain.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2012
    Trial
  5. Trial
  6. Article
  7. Article
  8. Can EQ-5D-3L utility values of low back pain patients be validly predicted by the Oswestry Disability Index for use in cost-effectiveness analyses?Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
  9. Review
  10. Observational
  11. Article
  12. Article
  13. Article
  14. A taxonomy of voice therapy.American journal of speech-language pathology · 2015
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Adri T ApeldoornDepartment of Epidemiology and Biostatistics and the EMGO Institute for Health and Care Research, VU University Medical Centre, Amsterdam, the Netherlands. a.apeldoorn@vumc.nl
Raymond W Ostelo
Hans van Helvoirt
Julie M Fritz
Henrika C W de Vet
Maurits W van Tulder
EMGO Institute for Health and Care Research · NLIntermountain Healthcare · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSystematic reviews have shown that exercise therapy and spinal manipulation are both more effective for low back pain (LBP) than no treatment at all. However, the effects are at best modest. To enhance the clinical outcomes, recommendations are to improve the patient selection process, and to identify relevant subgroups to guide clinical decision-making. One of the systems that has potentials to improve clinical decision-making is a treatment-based classification system that is intended to identify those patients who are most likely to respond to direction-specific exercises, manipulation, or stabilisation exercises. METHODS/

designThe primary aim of this randomised controlled trial will be to assess the effectiveness of a classification-based system. A sample of 150 patients with subacute and chronic LBP who attend a private physical therapy clinic for treatment will be recruited. At baseline, all participants will undergo a standard evaluation by trained research physical therapists and will be classified into one of the following subgroups: direction-specific exercises, manipulation, or stabilisation. The patient will not be informed about the results of the examination. Patients will be randomly assigned to classification-based treatment or usual care according to the Dutch LBP guidelines, and will complete questionnaires at baseline, and 8, 26, and 52 weeks after the start of the treatment. The primary outcomes will be general perceived recovery, functional status, and pain intensity. Alongside this trial, an economic evaluation of cost-effectiveness and cost-utility will be conducted from a societal perspective. DISCUSSION: The present study will contribute to our knowledge about the effectiveness and cost-effectiveness of classification-based treatment in patients with LBP.

trial registrationTRIAL REGISTRATION NUMBER: NTR1176.

Indexed as

AdolescentAdultAgedChronic DiseaseClassificationCost-Benefit AnalysisExercise TherapyHumansLow Back PainMiddle AgedNetherlandsOutcome Assessment, Health CarePatient SelectionPhysical Therapy ModalitiesQuality-Adjusted Life YearsRecovery of Function

Identifiers

PMID20346133
PMCPMC2859390
OpenAlexW1977821315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.