Evidence map›Paper›PMID 20346122›Full record

ArticleBMC cancer2010

Birth length and weight as predictors of breast cancer prognosis.

Bjørn O Maehle, Lars J Vatten, Steinar Tretli

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Antagonistic Pleiotropy in Human Disease.Journal of molecular evolution · 2020
    Review
  5. Medical record validation of maternal recall of pregnancy and birth events from a twin cohort.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2013
    Article
  6. The maternal womb: a novel target for cancer prevention in the era of the obesity pandemic?European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2011
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Bjørn O MaehleSection of Pathology, the Gade Institute, University of Bergen, Bergen, Norway. bjorn.mahle@gades.uib.no
Lars J Vatten
Steinar Tretli
Norwegian University of Science and Technology · NOUniversity of Bergen · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBirth size, and particularly birth length, is positively associated with breast cancer risk in adulthood. The objective of this study was to examine whether birth size is associated with survival among breast cancer patients.

methodsInformation on birth size (weight, length and ponderal index (kg/length (m3)) was collected from birth archives for 331 breast cancer patients who were diagnosed at two university hospitals in Norway (Bergen and Trondheim). The patients were followed from the time of diagnosis until death from breast cancer, death from another cause, or to the end of follow-up, and birth size was related to survival, using Cox regression analysis.

resultsBreast cancer patients with birth length > or = 52 cm had nearly twice the risk of dying (hazard ratio, 1.92, 95% confidence interval, 1.09-3.41) from breast cancer compared to women with birth length less than 48 cm, after adjustment for place of birth and year of diagnosis.Similar analyses related to birth weight and ponderal index showed no clear association with breast cancer survival.

conclusionsPoorer outcome of breast cancer patients with high birth length may reflect effects of factors that stimulate longitudinal growth and simultaneously increase the risk of metastases and fatal outcome. It is possible that the insulin-like growth factor (IGF) system is involved in the underlying mechanisms.

Indexed as

AdultAgedAged, 80 and overBirth WeightBody HeightBody WeightBreast NeoplasmsFemaleHumansInsulin-Like Growth Factor IMedical OncologyMiddle AgedPrognosisProportional Hazards ModelsTreatment OutcomeInsulin-Like Growth Factor I

Identifiers

PMID20346122
PMCPMC2851691
OpenAlexW2023164055

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.