Evidence map›Paper›PMID 20339999›Full record

ReviewMedical molecular morphology2010

Developments and applications of mass microscopy.

Mitsutoshi Setou, Kamlesh Shrivas, Morakot Sroyraya, Hyunjeong Yang, Yuki Sugiura, Junji Moribe, Akira Kondo, Koji Tsutsumi, Yoshishige Kimura, Nobuya Kurabe and 6 more

Abstract readReview
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In one paragraph

Review in Medical molecular morphology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Tumour Heterogeneity: The Key Advantages of Single-Cell Analysis.International journal of molecular sciences · 2016
    Review
  8. Review of matrix-assisted laser desorption ionization-imaging mass spectrometry for lipid biochemical histopathology.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2015
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Matrix-assisted laser desorption/ionization imaging mass spectrometry.International journal of molecular sciences · 2010
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Mitsutoshi SetouDepartment of Molecular Anatomy, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu, Shizuoka, 431-3192, Japan. setou@hama-med.ac.jp
Kamlesh Shrivas
Morakot Sroyraya
Hyunjeong Yang
Yuki Sugiura
Junji Moribe
Akira Kondo
Koji Tsutsumi
Yoshishige Kimura
Nobuya Kurabe
Takahiro Hayasaka
Naoko Goto-Inoue
Nobuhiro Zaima
Koji Ikegami
Prasert Sobhon
Yoshiyuki Konishi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have developed a mass microscopy technique, i.e., a microscope combined with high-resolution matrix-assisted laser desorption/ionization-imaging mass spectrometry (MALDI-IMS), which is a powerful tool for investigating the spatial distribution of biomolecules without any time-consuming extraction, purification, and separation procedures for biological tissue sections. Mass microscopy provides clear images about the distribution of hundreds of biomolecules in a single measurement and also helps in understanding the cellular profile of the biological system. The sample preparation and the spatial resolution and speed of the technique are all important steps that affect the identification of biomolecules in mass microscopy. In this Award Lecture Review, we focus on some of the recent developments in clinical applications to show how mass microscopy can be employed to assess medical molecular morphology.

Indexed as

AnimalsHumansImage EnhancementLipidsPharmaceutical PreparationsProteinsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationLipidsPharmaceutical PreparationsProteins

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.