ArticleInternational journal of dentistry2010
Sugar alcohols, caries incidence, and remineralization of caries lesions: a literature review.
Article in International journal of dentistry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 120 citations in OpenAlex.
- Sugar-free chewing gum's effect on patients receiving maintenance hemodialysis: a meta-analysis of RCTs.BMC nephrology · 2025Pooled it
- Effect of xylitol versus sorbitol: a quantitative systematic review of clinical trials.International dental journal · 2012Pooled it
- Anticariogenic effect of xylitol versus fluoride - a quantitative systematic review of clinical trials.International dental journal · 2012Pooled it
- A 12-Week Assessment of the Treatment of White Spot Lesions with CPP-ACP Paste and/or Fluoride Varnish.BioMed research international · 2016Trial
- Visual scoring of non cavitated caries lesions and clinical trial efficiency, testing xylitol in caries-active adults.Community dentistry and oral epidemiology · 2014Trial
- Results from the Xylitol for Adult Caries Trial (X-ACT).Journal of the American Dental Association (1939) · 2013Trial
- Enamel remineralization potential of bioactive glass-containing toothpastes: an in vitro study.Odontology · 2026Article
- Xylitol, Mitochondrial Plasticity, the Warburg Effect, and Oral Pathobiont-Associated Immune Evasion in Cancer Hypothesis.International journal of molecular sciences · 2026Review
- Microbial diversity and its links to retinol pathways and aroma compounds in ethnic fermented rice beverages of Assam.AMB Express · 2026Article
- Comparable Effectiveness of Novel and Commercial Saliva Substitute Gels in Dental Patients Experiencing Xerostomia: A Randomized, Double-Blind Crossover Trial.Gels (Basel, Switzerland) · 2026Article
- Comparison of Cariogenic Organic Acid Concentrations According to Combined Use of Sucrose and Sugar Alcohols.Journal of clinical medicine · 2025Article
- Effects of Chewing Gum on Plaque Index: A 3-Dimensional Colorimetric Analysis.Dentistry journal · 2025Article
- Assessing the Impact of Vegan Toothpastes on Enamel Color Change and Surface Properties.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025Article
- Unveiling the impact of allulose on oral microbiota and biofilm formation via a cariogenic potential assessment platform.Frontiers in cellular and infection microbiology · 2025Article
- Article
- Herbal medicines to prevent dental caries.The Cochrane database of systematic reviews · 2024Article
- Inhibition of incipient caries lesion progression by different fluoridated varnishes.Brazilian dental journal · 2024Article
- Evaluation of Solutions Containing Fluoride, Sodium Trimetaphosphate, Xylitol, and Erythritol, Alone or in Different Associations, on Dual-Species Biofilms.International journal of molecular sciences · 2023Article
- Genome-Wide Identification of Novel sRNAs in Streptococcus mutans.Journal of bacteriology · 2022Article
- Enzymatic Synthesis of Maltitol and Its Inhibitory Effect on the Growth ofBiomolecules · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Remineralization of minor enamel defects is a normal physiological process that is well known to clinicians and researchers in dentistry and oral biology. This process can be facilitated by various dietary and oral hygiene procedures and may also concern dentin caries lesions. Dental caries is reversible if detected and treated sufficiently early. Habitual use of xylitol, a sugar alcohol of the pentitol type, can be associated with significant reduction in caries incidence and with tooth remineralization. Other dietary polyols that can remarkably lower the incidence of caries include erythritol which is a tetritol-type alditol. Based on known molecular parameters of simple dietary alditols, it is conceivable to predict that their efficacy in caries prevention will follow the homologous series, that is, that the number of OH-groups present in the alditol molecule will determine the efficacy as follows: erythritol >/= xylitol > sorbitol. The possible difference between erythritol and xylitol must be confirmed in future clinical trials.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.