ReviewSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
Gastrointestinal and hepatic manifestations of primary immune deficiency diseases.
Review in Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 36 citations in OpenAlex.
- Primary Immunodeficiency Registry System: The Minimum Data Set Designing Phase-A Systematic Review and Quantitative Delphi Study.Health science reports · 2025Article
- HeterozygousInternational journal of molecular sciences · 2024Article
- High Inborn Errors of Immunity Risk in Patients with Granuloma.Journal of clinical immunology · 2022Article
- Gastrointestinal Disorders Associated with Primary Immunodeficiency Diseases.Clinical reviews in allergy & immunology · 2019Review
- Gastrointestinal Manifestations in X-linked Agammaglobulinemia.Journal of clinical immunology · 2017Article
- Exploring the sociodemographic and clinical features of extrapulmonary tuberculosis in Saudi Arabia.PloS one · 2015Article
- Attending to warning signs of primary immunodeficiency diseases across the range of clinical practice.Journal of clinical immunology · 2014Review
- Liver Abscesses and Hyper IgM Syndrome.Journal of family medicine and primary care · 2013Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary immune deficiency diseases (PIDs) are a heterogeneous group of inherited diseases characterized by variable genetic immune defects, conferring susceptibility to recurrent infections. They have a vast array of manifestations some of which involve the gastrointestinal and hepatobiliary systems. These complications can be the consequence of five different factors, namely, infection, autoimmune process, unregulated inflammation, malignancies and complications of therapeutic intervention. They may precede the PID diagnosis and, once developed, they pose high risk of morbidity. Untrained clinicians may treat these manifestations only at the level of their presentation, leaving the PIDs dangerously undiagnosed. In fact, early diagnosis of PIDs and accompanied gastrointestinal and hepatic complications clearly require appropriate treatment, and in-turn lead to an improved quality of life for the patient. To improve the awareness of gastroenterologists and related health care providers about these diseases, we have reviewed herein the complications of different PIDs focusing on gastrointestinal and hepatic manifestation.
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Registered trials
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