Evidence map›Paper›PMID 20337902›Full record

ArticleJournal of public health dentistry2010

Topical iodine and fluoride varnish combined is more effective than fluoride varnish alone for protecting erupting first permanent molars: a retrospective cohort study.

Ohnmar K Tut, Peter M Milgrom

Abstract readComparative Study
In one paragraph

Article in Journal of public health dentistry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Effect of a chlorhexidine/thymol and a fluoride varnish on caries development in erupting permanent molars: a comparative study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2015
    Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Observational
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ohnmar K TutMinistry of Health, Republic of the Marshall Islands.
Peter M Milgrom
University of Washington · US

Funding

Statistics and Data Coordinating CenterU54DE019346 · NIDCR · UNIVERSITY OF WASHINGTON · PI MANCL, LLOYD A · 2008 to 2012
$6.0M
NIDCR NIH HHS U54 DE019346NIDCR NIH HHS U54DE019346PHS HHS H47MC08647
6 · The paper itself

Abstract

objectiveThis communication examines the combined effect of topical polyvinylpyrollidone (PVP)-iodine plus fluoride varnish in the prevention of tooth decay in erupting first permanent molars in an ongoing public health program.

methodsThe evaluation employed a retrospective cohort design with two groups of children 60-83 months. Cohort 1 (2004-05) received three times per school year topical fluoride varnish, and Cohort 2 (2008-09) received topical application of 10 percent PVP-iodine followed at each visit with topical fluoride varnish. The children were examined clinically at the beginning and end of the school year.

resultsThe proportion of children with caries-free first permanent molars in Cohort 2 (PVP-iodine plus fluoride varnish) was 0.883 and was greater than that in Cohort 1 (varnish), which was 0.785 (Chi-square = 1.000E1, df 1, P < 0.002).

conclusionsThis evaluation of an ongoing dental public health program adds evidence that topical antiseptics applied at the same time as fluoride varnish are more effective than varnish alone. Randomized trials are needed.

Indexed as

Tooth EruptionAdministration, TopicalAnti-Infective Agents, LocalCariostatic AgentsChildChild, PreschoolCohort StudiesDental CariesDMF IndexDrug CombinationsFemaleFluoridesFluorides, TopicalFollow-Up StudiesHumansMaleAnti-Infective Agents, LocalCariostatic AgentsDrug CombinationsFluoridesFluorides, TopicalPovidone-IodineToothpastes

Identifiers

PMID20337902
PMCPMC2894298
OpenAlexW2171364154

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.