ArticleEuropean journal of applied physiology2010
Yearlong physical activity and sarcopenia in older adults: the Nakanojo Study.
Article in European journal of applied physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
75 citing papers in PubMed, 3 syntheses or guidelines pooled it, 157 citations in OpenAlex.
- A systematic review of the relationship between body composition including muscle, fat, bone, and body water and frailty in Asian residents.Nagoya journal of medical science · 2025Pooled it
- Statistical methods to model and evaluate physical activity programs, using step counts: A systematic review.PloS one · 2018Pooled it
- Relationship between sarcopenia and physical activity in older people: a systematic review and meta-analysis.Clinical interventions in aging · 2017Pooled it
- Sex differences in the associations of accelerometer-determined physical activity with physical and cognitive function in older adults living in long-term care.Frontiers in public health · 2024Trial
- Beneficial effects of walking-based home program for improving cardio-respiratory performance and physical activity in sarcopenic older people: a randomized controlled trial.European journal of physical and rehabilitation medicine · 2022Trial
- Multi-Component Intervention Program on Habitual Physical Activity Parameters and Cognitive Function in Patients with Mild Cognitive Impairment: A Randomized Controlled Trial.International journal of environmental research and public health · 2021Trial
- Trial
- Six-month walking program changes cognitive and ADL performance in patients with Alzheimer.American journal of Alzheimer's disease and other dementias · 2011Trial
- Tissue-specific body composition changes and muscle performance decline: a 5-year prospective study.Aging clinical and experimental research · 2026Article
- Longitudinal Effects of Snow-season Activity Decline on Physical Function in Older Adults in Rural Snowy Regions.Physical therapy research · 2026Article
- Physical activity associations with physical function and body composition among community-dwelling older adults in Japan: The Kyotango Longevity Cohort Study.Geriatrics & gerontology international · 2025Article
- Possible involvement of p60-S6K1 in accelerating RPS6 phosphorylation for rapid recovery from skeletal muscle disuse atrophy.Laboratory animal research · 2025Article
- Observational
- Nonleisure-time physical activity as a protective factor against sarcopenia in hemodialysis patients: a prospective cohort study.Frontiers in nutrition · 2025Article
- Cross-sectional association of physical activity levels with risks of sarcopenia among older Taiwanese adults.BMC geriatrics · 2024Article
- Replacing sedentary time for physical activity: Does intensity matter for body composition in oldest-old adults?Journal of sports sciences · 2024Article
- The Effect of Web-Based Culinary Medicine to Enhance Protein Intake on Muscle Quality in Older Adults: Randomized Controlled Trial.JMIR formative research · 2024Article
- Prevalence and associated factors of frailty in patients with chronic kidney disease: a cross-sectional analysis of PEAKING study.International urology and nephrology · 2024Article
- Machine Learning Applications in Sarcopenia Detection and Management: A Comprehensive Survey.Healthcare (Basel, Switzerland) · 2023Article
- Sarcopenia parameters in active older adults - an eight-year longitudinal study.BMC public health · 2023Observational
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We tested the hypothesis that a low level of regular daily physical activity in elderly individuals would be associated with a clinically significant degree of sarcopenia. Subjects were 78 male and 97 female free-living Japanese, aged 65-84 years. A pedometer/accelerometer measured continuously the number of steps taken and the intensity of activity 24 h/day for 1 year. A whole-body dual X-ray absorptiometry scan assessed skeletal muscle mass in the upper and lower extremities at the end of the year. Sarcopenia was defined as a muscle mass/height(2) value >1 SD below the mean for healthy young Japanese. Linear and exponential regressions showed that after controlling data for age and/or sex, muscle mass was associated with physical activity, more closely for the legs than for the arms, and for duration of moderate activity (>3 METs) than for step count. Muscle mass increased progressively with daily activity, although when data were categorized into quartiles, muscle mass was not significantly greater in men and women who exceeded, respectively, 8,000 and 6,900 steps/day and/or 22 and 19 min/day at >3 METs. All participants meeting such criteria exceeded our sarcopenia threshold. Multivariate-adjusted logistic regressions predicted that individuals who walked <5,300 steps/day and/or spent <15 min/day at >3 METs were, respectively, 2.00-2.66 and/or 2.03-4.55 times more likely to show sarcopenia than those who walked >7,800 steps/day and/or spent >23 min/day at >3 METs. Our hypothesis was proven correct: seniors who walked at least 7,000-8,000 steps/day and/or spent 15-20 min/day at an intensity of >3 METs were likely to have a muscle mass above the sarcopenia threshold.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.