ReviewApplied microbiology and biotechnology2010
Rhamnolipids: diversity of structures, microbial origins and roles.
Review in Applied microbiology and biotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 298 papers.
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Who cites it
298 citing papers in PubMed, 929 citations in OpenAlex.
- Enhancing acetate-based biosurfactant production by Pseudomonas putida KT2440 through fermentation optimization.Microbial cell factories · 2026Article
- Morphology Evolution and Structural Reorganization of Enzyme-Biosurfactant Systems: Implications for Petroleum Interfacial Engineering.Polymers · 2026Article
- Biosurfactant-Based Interventions for Improving Lung Function and Controlling Inflammation.Pharmaceutical research · 2026Review
- Metabolomic-Metabolite Profiling: Progressive Insight and Biochemical Pathway in Crude Oil Waste Sludge Co-Composting Bioremediation.Metabolites · 2026Article
- Rhamnolipid-augmented medium enhances growth ofApplied and environmental microbiology · 2026Article
- Isolation and Characterization of Biosurfactants from Bacillus sp. and Rosellomorea sp. and their Application for Removal of Chromium Level in Vegetable Crops.Current microbiology · 2026Article
- Quorum sensing inhibition strategies for the control of Pseudomonas aeruginosa infections.World journal of microbiology & biotechnology · 2026Review
- Multidomain DNA-Protein Mining Reveals Polymorphic Variations in RhlB Enhancing Monorhamnolipid Biosynthesis.ACS synthetic biology · 2026Article
- The post-translational adaptor protein SadB modulates the pathogenicity ofJournal of bacteriology · 2026Article
- Development of Mild Palladium-Catalyzed N-Arylation of Ortho-Acylanilines in Rhamnolipid Micellar System.ChemSusChem · 2026Article
- Variovoracins: new glycolipopeptide biosurfactants identified by surfactant screening and genome mining.RSC advances · 2026Article
- Review in Structure-Activity Relationships, Synthetic Regulation, and Applications of Mono/Di-Rhamnolipids.Microorganisms · 2026Review
- Multilocus sequence typing and genomic characterization of the novel Streptomyces strain SCPE-10, that resists 2,4-D toxicity and has bioremediation potential.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Rhamnolipid-Like Glycolipid Biosurfactant fromJournal of microbiology and biotechnology · 2026Article
- Actinomycetes in the spotlight: biodiversity and their role in bioremediation.World journal of microbiology & biotechnology · 2026Review
- Concentrated Rhamnolipid Formulations: Bridging Chemodiversity to Structure, Flow Behavior, and Functionality.ACS sustainable chemistry & engineering · 2026Article
- Activity evaluation and composition analysis of biosurfactants produced by an obligate cold-adapted bacterium Pedobacter sp. NJ-S-72 isolated from Antarctica.World journal of microbiology & biotechnology · 2026Article
- Cost-Effective rhamnolipids production from corn Bran and their application in essential oil extraction.World journal of microbiology & biotechnology · 2026Article
- Development and Evaluation of Bio-Based Anionic Surfactants from Corn Oil for Corrosion Protection of Mild Steel.ACS omega · 2025Article
- PqsE has a conserved sequence, yet a variable impact inJournal of bacteriology · 2025Article
238 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rhamnolipids are glycolipidic biosurfactants produced by various bacterial species. They were initially found as exoproducts of the opportunistic pathogen Pseudomonas aeruginosa and described as a mixture of four congeners: alpha-L-rhamnopyranosyl-alpha-L-rhamnopyranosyl-beta-hydroxydecanoyl-beta-hydroxydecanoate (Rha-Rha-C(10)-C(10)), alpha-L-rhamnopyranosyl-alpha-L-rhamnopyranosyl-beta-hydroxydecanoate (Rha-Rha-C(10)), as well as their mono-rhamnolipid congeners Rha-C(10)-C(10) and Rha-C(10). The development of more sensitive analytical techniques has lead to the further discovery of a wide diversity of rhamnolipid congeners and homologues (about 60) that are produced at different concentrations by various Pseudomonas species and by bacteria belonging to other families, classes, or even phyla. For example, various Burkholderia species have been shown to produce rhamnolipids that have longer alkyl chains than those produced by P. aeruginosa. In P. aeruginosa, three genes, carried on two distinct operons, code for the enzymes responsible for the final steps of rhamnolipid synthesis: one operon carries the rhlAB genes and the other rhlC. Genes highly similar to rhlA, rhlB, and rhlC have also been found in various Burkholderia species but grouped within one putative operon, and they have been shown to be required for rhamnolipid production as well. The exact physiological function of these secondary metabolites is still unclear. Most identified activities are derived from the surface activity, wetting ability, detergency, and other amphipathic-related properties of these molecules. Indeed, rhamnolipids promote the uptake and biodegradation of poorly soluble substrates, act as immune modulators and virulence factors, have antimicrobial activities, and are involved in surface motility and in bacterial biofilm development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.