ArticleMolecules (Basel, Switzerland)2010
Antimicrobial, cytotoxicity and phytochemical screening of Jordanian plants used in traditional medicine.
Article in Molecules (Basel, Switzerland), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 210 citations in OpenAlex.
- Phytochemical profiling and in-vitro antibacterial activity of Croton macrostachyus Hochst. ex Delile leaf and stem bark extracts against selected human pathogens.Scientific reports · 2026Article
- Article
- Article
- Chromatographic Isolation, Characterization and in vitro Cytotoxic Evaluation of Ageratum Conyzoides L.Current microbiology · 2025Article
- Evaluation of Antibacterial Activity of Trichilia dregeana Sond. (Meliaceae) Methanolic Extract Against Gram-Positive and Gram-Negative Bacteria.Veterinary medicine and science · 2025Article
- Potential immunomodulatory effects of the extract fromFrontiers in genetics · 2025Article
- Phytochemical Content of Malus floribunda: In Vitro and Molecular Docking Studies.Applied biochemistry and biotechnology · 2024Article
- A comprehensive review on ethnomedicinal uses, phytochemistry, toxicology, and pharmacological activities ofJournal of traditional and complementary medicine · 2024Review
- In vitro antibacterial activity of Bersama abyssinica Fresen crude extract against representative Gram-positive and Gram-negative bacterial isolates.Veterinary medicine and science · 2024Article
- Anti-Food science & nutrition · 2024Article
- The In Vitro Assessment of Antibacterial and Antioxidant Efficacy inMicroorganisms · 2023Article
- Phytochemical Profile, Antioxidant Potential, Antimicrobial Activity, and Cytotoxicity of Dry Extract fromMolecules (Basel, Switzerland) · 2023Article
- Medicinal plants of Jordan: Scoping review.Heliyon · 2023Article
- Phytochemicals: potential alternative strategy to fightFrontiers in veterinary science · 2023Review
- Antibacterial Activity ofJournal of microbiology and biotechnology · 2022Article
- Article
- Role of phytobiotics in relieving the impacts ofFrontiers in veterinary science · 2022Review
- Gaz Alafi: A Traditional Dessert in the Middle East With Anticancer, Immunomodulatory, and Antimicrobial Activities.Frontiers in nutrition · 2022Article
- Bioactive Constituents and Toxicological Evaluation of Selected Antidiabetic Medicinal Plants of Saudi Arabia.Evidence-based complementary and alternative medicine : eCAM · 2022Review
- Comparison of Phytochemical Contents, Antioxidant and Antibacterial Activities of Various Solvent Extracts Obtained from 'Maluma' Avocado Pulp Powder.Molecules (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antimicrobial activity and cytotoxicity of fifty one extracts of different parts of 14 plants were studied. Ethanol, methanol, aqueous, butanol, and n-hexane extracts were tested against three gram negative, two gram positive bacteria, and two fungi. Cytotoxicity and phytochemical screening were determined using MTT and TLC assays, respectively. Of the fifty one extracts, twenty two showed activities against different microorganisms with MICs ranging from 62.5 to 1000 microg/mL. The highest activity (100% inhibition) was for a butanol extract of Rosa damascena receptacles against Salmonella typhimurium and Bacillus cereus (MIC of 62.5 and 250 microg/mL) respectively. Butanol extract of Narcissus tazetta aerial parts and aqueous extract of Rosa damascena receptacles were both active against Candida albicans (MIC of 125 microg/mL). Methicillin-resistant Staphylococcus aureus was inhibited by butanol, aqueous extracts of Rosa damascena receptacles and butanol extract of Inula viscosa flowers (MIC of 500, 500, and 250 microg/mL) respectively. Rosa damascena receptacles and Verbascum sinaiticum flowers ethanol extract showed lowest cytotoxicity against Vero cell line (IC50 of 454.11 and 367.11). Most toxic was the ethanol extract of Ononis hirta aerial parts (IC50 72.50 microg/mL). Flavonoids and terpenoids were present in all plants. Ononis hirta and Narcissus tazetta contained alkaloids. The results validate the use of these plants and report for the first time bioactivity of Rosa damascena receptacles and further justifies the use of such screening programs in the quest for new drugs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.