Evidence map›Paper›PMID 20336007›Full record

ArticleMolecules (Basel, Switzerland)2010

Influence of magnolol on the secretion of alpha-toxin by Staphylococcus aureus.

Hua Xiang, Jia-Zhang Qiu, Da-Cheng Wang, You-Shuai Jiang, Li-Jie Xia, Xu-Ming Deng

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The promising anti-virulence activity of candesartan, domperidone, and miconazole on Staphylococcus aureus.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022
    Article
  5. Medicinal Chemistry of Inhibitors Targeting Resistant Bacteria.Current topics in medicinal chemistry · 2022
    Article
  6. Control of FoodborneFoods (Basel, Switzerland) · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Biosynthesis of Silver Nanoparticles usingAvicenna journal of medical biotechnology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hua XiangInstitute of Zoonoses, College of Animal Sciences and Veterinary Medicine, Jilin University, Changchun, Jilin 130062, China. xianghuaxh@126.com
Jia-Zhang Qiu
Da-Cheng Wang
You-Shuai Jiang
Li-Jie Xia
Xu-Ming Deng
Jilin University · CNHeilongjiang Bayi Agricultural University · CNYangzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study we investigated the antimicrobial activity of magnolol on Staphylococcus aureus. The minimal inhibitory concentrations of magnolol against 31 S. aureus strains ranged from 4-32 microg/mL. In addition, hemolysin assays, Western blotting, and real-time RT-PCR were performed to investigate the effect of magnolol on alpha-toxin secretion by both methicillin-sensitive S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA). The results indicated that sub-inhibitory concentrations of magnolol dose-dependently inhibited the transcription of hla (the gene encoding alpha-toxin) in S. aureus, resulting in a reduction of alpha-toxin secretion and, thus, hemolytic activities.

Indexed as

AnimalsBacterial ToxinsBiphenyl CompoundsBlotting, WesternHemolysin ProteinsHemolysisLignansRabbitsReverse Transcriptase Polymerase Chain ReactionStaphylococcus aureusBacterial ToxinsBiphenyl CompoundsHemolysin ProteinsLignansmagnololstaphylococcal alpha-toxin

Identifiers

PMID20336007
PMCPMC6257330
OpenAlexW2120593137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.