ReviewExercise and sport sciences reviews2010
Mechanisms behind estrogen's beneficial effect on muscle strength in females.
Review in Exercise and sport sciences reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07591818 (Menstrual Cycle and Oral Contraceptive Use in Athletic Performance and Health-related Hydration and Energy Balance Status), which is not on this map. Cited by 70 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Menstrual Cycle and Oral Contraceptive Use in Athletic Performance and Health-related Hydration and Energy Balance Status
Who cites it
70 citing papers in PubMed, 4 syntheses or guidelines pooled it, 190 citations in OpenAlex.
- Menstrual Cycle and Sport Injuries: A Systematic Review.International journal of environmental research and public health · 2023Pooled it
- The Effects of Menstrual Cycle Phase on Exercise Performance in Eumenorrheic Women: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2020Pooled it
- The Effect of the Menstrual Cycle and Oral Contraceptives on Acute Responses and Chronic Adaptations to Resistance Training: A Systematic Review of the Literature.Sports medicine (Auckland, N.Z.) · 2020Pooled it
- Intracrine and myotrophic roles of 5α-reductase and androgens: a review.Medicine and science in sports and exercise · 2012Pooled it
- Effects of Hormonal Contraception and the Menstrual Cycle on Maximal Strength and Power Performance.Medicine and science in sports and exercise · 2024Trial
- Shatavari Supplementation in Postmenopausal Women Improves Handgrip Strength and IncreasesNutrients · 2021Trial
- Preventive effects of raloxifene treatment on agerelated weight loss in postmenopausal women.Journal of bone and mineral metabolism · 2017Trial
- Body composition and bone mineral density after ovarian hormone suppression with or without estradiol treatment.Menopause (New York, N.Y.) · 2015Trial
- The hallmarks of skeletal muscle health.Nature metabolism · 2026Review
- Changes in physical performance with aging in master athletes and in the general population: an update.European journal of translational myology · 2026Article
- Association Between Hormone Therapy and Health-Related Quality of Life in Postmenopausal Korean Women: A Nationwide Cross-Sectional Study Using 2005-2009 KNHANES Data.Healthcare (Basel, Switzerland) · 2026Article
- Comparative Responses of Self-Regulated Exercise, Thermoregulation, and Neuromuscular Function to Monophasic Oral Contraceptives Across One Menstrual Cycle.European journal of sport science · 2026Article
- Children'sEuropean journal of applied physiology · 2025Review
- Exploring the torque- velocity relationship in postmenopausal women: Analyzing the influence of data processing.PloS one · 2025Article
- Exercise performance at different phases of the menstrual cycle: measurements, differences, and mechanisms - a narrative review.Frontiers in endocrinology · 2025Review
- Muscle function, exercise capacity, physical activity level and cardiovascular disease risk factor knowledge in patients with prolactinoma.Endocrine · 2024Observational
- At What Point in the Menstrual Cycle Are the Pelvic Floor Muscles at Their Weakest?Journal of functional morphology and kinesiology · 2024Article
- Mouse sarcopenia model reveals sex- and age-specific differences in phenotypic and molecular characteristics.The Journal of clinical investigation · 2024Article
- Influence of the Menstrual Cycle and Training on the Performance of a Perturbed Single-Leg Squatting Task in Female Collegiate Athletes.Orthopaedic journal of sports medicine · 2024Article
- Modified Squat Test for Predicting Knee Muscle Strength in Older Adults.Annals of geriatric medicine and research · 2024Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Muscle weakness ensues when serum testosterone declines with age in men. Testosterone's female counterpart, estrogen, also has been implicated in age-related strength loss, but these results are less conclusive. Our working hypothesis is that estrogens do benefit muscle strength, and that the underlying mechanism involves estrogen receptors to improve muscle quality more so than quantity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.