Evidence map›Paper›PMID 20335542›Full record

ReviewThe American journal of clinical nutrition2010

Childhood obesity and adult morbidities.

Frank M Biro, Michelle Wien

2 registry-linked trialsOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The American journal of clinical nutrition, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 403 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
403citing papers in PubMed, 9 pooled it
71.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03766191 nacompletednot on this mapstarted 2019, after this paper: background citation

The Relation of Genetic Factors, Food Cues, and Self-Regulation With Excess Consumption and Adiposity in Children

TypeinterventionalSponsorTrustees of Dartmouth CollegeRan2019 to 2024Enrolled189ConditionsChildhood ObesityArmsFood Ads, Non-food Ads
NCT03882957 nacompletednot on this mapstarted 2019, after this paper: background citation

Media Multi-tasking and Cued Overeating: Assessing the Pathway and Piloting an Intervention Using an Attentional Network Framework

TypeinterventionalSponsorDartmouth-Hitchcock Medical CenterRan2019 to 2020Enrolled92ConditionsAttention Concentration Difficulty, Obesity, ChildhoodArmsSustained attention, media multi-task, Video
3 · Its place in the literature

Who cites it

403 citing papers in PubMed, 9 syntheses or guidelines pooled it, 1,075 citations in OpenAlex.

  1. Epigenetic Mechanisms in Childhood Obesity.Annals of the New York Academy of Sciences · 2025
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  14. Reducing Obesogenic Eating Behaviors in Hispanic Children through a Family-Based, Culturally-Tailored RCT:International journal of environmental research and public health · 2022
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343 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Frank M BiroUniversity of Cincinnati College of Medicine, Division of Adolescent Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA. frank.biro@cchmc.org
Michelle Wien
Cincinnati Children's Hospital Medical Center · US

Funding

Puberty &Cancer Initiation: Environment Diet &ObesityU01ES012770 · NIEHS · UNIVERSITY OF CINCINNATI · PI BORNSCHEIN, ROBERT L · 2003 to 2009
$9.0M
NIEHS NIH HHS U01 ES012770NIEHS NIH HHS U01-ES12770
6 · The paper itself

Abstract

The prevalence and severity of obesity have increased in recent years, likely the result of complex interactions between genes, dietary intake, physical activity, and the environment. The expression of genes favoring the storage of excess calories as fat, which have been selected for over many millennia and are relatively static, has become maladaptive in a rapidly changing environment that minimizes opportunities for energy expenditure and maximizes opportunities for energy intake. The consequences of childhood and adolescent obesity include earlier puberty and menarche in girls, type 2 diabetes and increased incidence of the metabolic syndrome in youth and adults, and obesity in adulthood. These changes are associated with cardiovascular disease as well as with several cancers in adults, likely through insulin resistance and production of inflammatory cytokines. Although concerns have arisen regarding environmental exposures, there have been no formal expert recommendations. Currently, the most important factors underlying the obesity epidemic are the current opportunities for energy intake coupled with limited energy expenditure.

Indexed as

AdolescentAdultAlcohol DrinkingBody Mass IndexChildDiabetes Mellitus, Type 2Disease OutbreaksEnergy IntakeEnergy MetabolismFemaleHumansMaleMenarcheMetabolic SyndromeMiddle AgedMorbidity

Identifiers

PMID20335542
PMCPMC2854915
OpenAlexW2162200202

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.