Evidence map›Paper›PMID 20333784›Full record

ReviewWorld journal of gastroenterology2010

Celiac disease in Middle Eastern and North African countries: a new burden?

Kassem Barada, Abbas Bitar, Mohamad Abdul-Razak Mokadem, Jana Ghazi Hashash, Peter Green

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 119 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  14. Consensus Statement by an Expert Panel on the Diagnosis and Management of Iron Deficiency Anemia in the Gulf Cooperation Council Countries.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2020
    Article
  15. Article
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  17. Review
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  19. Coeliac disease: to biopsy or not?Nature reviews. Gastroenterology & hepatology · 2018
    Review
  20. Gluten-free products in celiac disease: Nutritional and technological challenges and solutions.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kassem BaradaDivision of Gastroenterology, Department of Internal Medicine, American University of Beirut Medical Center, PO Box 11-0236, Beirut 110 72020, Lebanon. kb02@aub.edu.lb
Abbas Bitar
Mohamad Abdul-Razak Mokadem
Jana Ghazi Hashash
Peter Green
American University of Beirut Medical Center · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Celiac disease (CD) is now recognized as a common disorder among Middle Eastern (ME) and North African (NA) populations. The aim of this review is to assess the available data regarding CD in the ME and NA and to compare this information with that of Western countries. A literature review was performed using the electronic databases PubMed and Medline (1950-2008) as search engines, and "celiac disease" was used as a Mesh term. The search was limited to ME and NA countries. The prevalence of CD in ME and NA countries among low risk populations is similar to that of Western countries, but is higher in high risk populations such as those with type 1 diabetes. It is underestimated because of lack of clinical suspicion and lack of patient awareness. Clinical presentations in term of gastrointestinal, hematologic, skeletal, and liver manifestations are similar between both populations except for a high prevalence of short stature in some ME and NA countries. Few studies have addressed atypical or silent CD. As in the West, diagnosis is initially made by serological tests and is confirmed by small intestinal biopsies. Gluten-free diet is the main mode of treatment with a higher apparent adherence rate than in the West. Most disease complications result from malabsorption. The disease is strongly associated with HLA DQ2 and to a lesser extent with HLA DQ8 alleles. In conclusion, CD prevalence is underestimated, with little data available about its malignant complications. Disease parameters in the ME and NA are otherwise similar to those in Western countries.

Indexed as

Developing CountriesAdolescentAdultAfrica, NorthernCeliac DiseaseChildDiet, Gluten-FreeGenetic Predisposition to DiseaseHumansMiddle EastPredictive Value of TestsPrevalenceRisk AssessmentRisk FactorsTreatment OutcomeYoung Adult

Identifiers

PMID20333784
PMCPMC2846249
OpenAlexW2113500977

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.