ReviewAngewandte Chemie (International ed. in English)2010
Silicon-based cross-coupling reactions in the total synthesis of natural products.
Review in Angewandte Chemie (International ed. in English), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 284 citations in OpenAlex.
- Palladium(II)/Norbornene Cooperative Catalysis for Regioselective C-H Silylation Toward Diversified Silylindoles.Molecules (Basel, Switzerland) · 2026Article
- Visible-Light-Mediated Metal-Free Desulfonylative Silylation for Alkenyl and Alkynylsilanes with Silacarboxylic Acids.ACS omega · 2026Article
- Advancing total synthesis through the Stille cross-coupling: recent innovations and case studies.RSC advances · 2026Review
- Stereospecific cross-coupling reactions: Programmed assembly of chiral molecules by reaction of chiral reagents.Science advances · 2025Review
- Deoxygenative Functionalization of Alcohols and Carbonyl Compounds via Electrochemical Reduction.Angewandte Chemie (International ed. in English) · 2025Article
- Green and Sustainable Synthesis of Biaryls Using LaPOACS omega · 2025Article
- Harnessing the β-boron effect for regioselective Ru-catalyzed hydrosilylation of internal alkynes.Nature communications · 2025Article
- Iridium-Catalyzed, Site-Selective Silylation of Secondary C(spJournal of the American Chemical Society · 2023Article
- Stereoselective C-O silylation and stannylation of alkenyl acetates.Nature communications · 2023Article
- Development of a General Method for the Hiyama-Denmark Cross-Coupling of Tetrasubstituted Vinyl Silanes.ACS catalysis · 2022Article
- Photocatalytic E→Z Contra-Thermodynamic Isomerization of Vinyl Silanes with Lewis Base.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Transition Metal Catalyzed Hiyama Cross-Coupling: Recent Methodology Developments and Synthetic Applications.Molecules (Basel, Switzerland) · 2022Review
- Potassium Trimethylsilanolate-Promoted, Anhydrous Suzuki-Miyaura Cross-Coupling Reaction Proceeds via the "Boronate Mechanism": Evidence for the Alternative Fork in the Trail.Journal of the American Chemical Society · 2022Article
- Inorganometallics (Transition Metal-Metalloid Complexes) and Catalysis.Chemical reviews · 2022Review
- Cross-coupling reactions towards the synthesis of natural products.Molecular diversity · 2022Review
- Crystal structure and Hirshfeld surface analysis of 1-[(benzyl-dimethyl-sil-yl)meth-yl]-1-ethyl-piperidin-1-ium ethane-sulfonate.Acta crystallographica. Section E, Crystallographic communications · 2022Article
- Hydrosilane σ-Adduct Intermediates in an Adaptive Zinc-Catalyzed Cross-dehydrocoupling of Si-H and O-H Bonds.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Article
- A Green Synthesis Strategy of Binuclear Catalyst for the C-C Cross-Coupling Reactions in the Aqueous Medium: Hiyama and Suzuki-Miyaura Reactions as Case Studies.Frontiers in chemistry · 2021Article
- Solvent-free synthesis of enantioenriched β-silyl nitroalkanes under organocatalytic conditions.Beilstein journal of organic chemistry · 2021Article
- A Modular, Enantioselective Synthesis of Resolvins D3, E1, and Hybrids.Organic letters · 2020Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Unlike other variants of transition-metal-catalyzed cross-coupling reactions, those based on organosilicon donors have not been used extensively in natural product synthesis. However, recent advances such as: 1) the development of mild reaction conditions, 2) the expansion of substrate scope, 3) the development of methods to stereoselectively and efficiently introduce the silicon-containing moiety, 4) the development of a large number of sequential processes, and 5) the advent of bifunctional bis(silyl) linchpin reagents, signify the coming of age of silicon-based cross-coupling reactions. The following case studies illustrate how silicon-based cross-coupling reactions play a strategic role in constructing carbon-carbon bonds in selected target molecules.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.