ArticleClinical orthopaedics and related research2010
Nonadherence in outpatient thrombosis prophylaxis with low molecular weight heparins after major orthopaedic surgery.
Article in Clinical orthopaedics and related research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Effectiveness and safety of rivaroxaban or low-molecular-weight heparin in non-major orthopedic surgery: a meta-analysis of randomized controlled trials.Journal of orthopaedic surgery and research · 2024Pooled it
- Superficial vein thrombosis treated for 45 days with rivaroxaban versus fondaparinux: rationale and design of the SURPRISE trial.Journal of thrombosis and thrombolysis · 2016Trial
- Efficacy and safety of rivaroxaban versus low-molecular-weight heparin therapy in patients with lower limb fractures.Journal of thrombosis and thrombolysis · 2014Trial
- Rivaroxaban vs. enoxaparin for preventing venous thromboembolism after hip fracture operations: a retrospective cohort study.Frontiers in surgery · 2025Article
- Is It Safe to Resume Direct Oral Anticoagulants upon Discharge after Hip Fracture Surgery? A Retrospective Study.Journal of clinical medicine · 2023Article
- Inpatient compliance with venous thromboembolism prophylaxis after orthopaedic trauma: results from a randomized controlled trial of aspirin versus low molecular weight heparin.OTA international : the open access journal of orthopaedic trauma · 2021Article
- Extended thromboprophylaxis for hip or knee arthroplasty. Does the administration route and dosage regimen affect adherence? A cohort study.International orthopaedics · 2020Article
- Dabigatran (Pradaxa) Is Safe for Extended Venous Thromboembolism Prophylaxis After Surgery for Pancreatic Cancer.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019Article
- Aspirin: are patients actually taking it?-A quality assessment study.Arthroplasty today · 2018Article
- Effects of Natural Hirudin and Low Molecular Weight Heparin in Preventing Deep Venous Thrombosis in Aged Patients with Intertrochanteric Fracture.Scientific reports · 2018Article
- Venous Thromboembolism Prophylaxis After TKA: Aspirin, Warfarin, Enoxaparin, or Factor Xa Inhibitors?Clinical orthopaedics and related research · 2017Article
- Patients' perceptions and experiences of the prevention of hospital-acquired thrombosis: a qualitative study.BMJ open · 2016Article
- Patient Adherence and Experience with Extended Use of Prophylactic Low-Molecular-Weight Heparin Following Pancreas and Liver Resection.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2016Article
- Prevention of hospital-acquired thrombosis from a primary care perspective: a qualitative study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2016Article
- The compliance of thromboprophylaxis affects the risk of venous thromboembolism in patients undergoing hip fracture surgery.SpringerPlus · 2016Article
- Validation of the Adherence Barriers Questionnaire - an instrument for identifying potential risk factors associated with medication-related non-adherence.BMC health services research · 2015Article
- Continuation of venous thromboembolism prophylaxis after hospital discharge into the outpatient setting: the ACCEPT study.Journal of thrombosis and thrombolysis · 2015Observational
- Current and emerging strategies in the management of venous thromboembolism: benefit-risk assessment of dabigatran.Vascular health and risk management · 2015Review
- Efficacy and safety of venous thromboembolism prophylaxis with apixaban in major orthopedic surgery.Therapeutics and clinical risk management · 2012Article
- [Patient pathways in thrombosis prophylaxis after hip and knee replacement surgery : results of a survey].Der Orthopade · 2011Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAccording to some current guidelines, extended thromboprophylaxis after hip and knee arthroplasties is recommended. Outpatient prophylaxis with low molecular weight heparins (LMWH) is an important part of this prophylaxis, although the rates of adherence to these regimens is not known. QUESTIONS/PURPOSES: We determined (1) the degree of nonadherence (NA) of patients with LMWH outpatient prophylaxis, and (2) whether specific independent factors explain NA.
methodsNA was determined by syringe count and by indirect and direct questions to patients. We defined six different NA indicators. To identify factors explaining LMWH NA, we used three different logistic regression models.
resultsNA rates ranged between 13% and 21% depending on the indicator used for measurement. Patients who were nonadherent missed between 38% and 53% of their outpatient LMWH injections. If patients attended an outpatient rehabilitation program, the probability for their NA increased substantially. Moreover, the NA probability increased with each additional day between acute hospitalization and start of rehabilitation (linking days). NA was lower for patients who feared thrombosis or who believed antithrombotic drugs to be the most important measure in thromboprophylaxis. LEVEL OF EVIDENCE: Level II, prognostic study. See the Guidelines for Authors for a complete description of levels of evidence.
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