ReviewClinical research in cardiology : official journal of the German Cardiac Society2010
Cardiac manifestation of the hypereosinophilic syndrome: new insights.
Review in Clinical research in cardiology : official journal of the German Cardiac Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.
- Loeffler endocarditis with intracardiac thrombus: case report and literature review.BMC cardiovascular disorders · 2021Pooled it
- Risk factors for thrombosis in eosinophilia: A case-control study.Scientific reports · 2026Article
- Article
- Organ-Restricted Hypereosinophilic Syndrome: A Case of Recurrent Hypereosinophilic Myopericarditis.JACC. Case reports · 2025Article
- Advancing clinical management of left ventricular thrombosis: prevention, detection and treatment modalities in the modern era.Heart (British Cardiac Society) · 2025Review
- Four challenging cases of eosinophilic endocarditis or myocarditis with literature review.Journal of cardiothoracic surgery · 2025Review
- Case Report: Idiopathic hypereosinophilic syndrome presenting with gastrointestinal involvement mimicking IBD: a diagnostic challenge.Frontiers in medicine · 2025Article
- Approach to the patient with eosinophilia in the era of tyrosine kinase inhibitors and biologicals.Current hematologic malignancy reports · 2024Review
- Review
- Hypereosinophilic syndrome: a rare cause of ST-elevation myocardial infarction and thrombus formation on the aortic valve.BMJ case reports · 2024Article
- Cardiac Mechanics and Valvular and Vascular Abnormalities in Hypereosinophilic Syndrome.Journal of clinical medicine · 2024Review
- Two Different Clinical Presentations and Stages of Loeffler Endocarditis Diagnosed by Multimodality Investigations.CASE (Philadelphia, Pa.) · 2023Article
- Myocardial acoustics-assisted diagnosis of right ventricular Loeffler endocarditis.Quantitative imaging in medicine and surgery · 2023Article
- Endomyocardial Fibrosis With Bilateral Ventricular Thrombus: A Case Report and Literature Review.Cureus · 2023Article
- Mitral and Tricuspid Annular Abnormalities in Hypereosinophilic Syndrome-Insights from the Three-Dimensional Speckle-Tracking Echocardiographic MAGYAR-Path Study.Reviews in cardiovascular medicine · 2023Article
- At the Heart of Eosinophilic Granulomatosis with Polyangiitis: into Cardiac and Vascular Involvement.Current rheumatology reports · 2022Review
- Loeffler Endocarditis Causing Heart Failure with Preserved Ejection Fraction (HFpEF): Characteristic Images and Diagnostic Pathway.Diagnostics (Basel, Switzerland) · 2022Article
- Hypereosinophilic Syndrome with Advanced-Stage Loeffler Endocarditis.CASE (Philadelphia, Pa.) · 2022Article
- Drug Treatment of Heart Failure in Children: Gaps and Opportunities.Paediatric drugs · 2022Review
- Case report: Different clinical manifestations of the rare Loeffler endocarditis.Frontiers in cardiovascular medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiac manifestation is the major cause of morbidity in patients with hypereosinophilic syndrome (HES). Clinical features range from heart failure to arterial embolism, which are caused by thickening of the endocardium and mural left ventricular thrombosis. Modern magnetic resonance imaging and echocardiography are able to detect fibrosis, eosinophilic infiltrate and thrombi to stage the fibrotic evolution of the disease. Treatment of HES involves standard medication for heart failure, anticoagulant therapy, immunosuppressive therapy and potentially surgical resection. The outcome of HES depends on both the progression of endocardial fibrosis and associated complications and the 5-year mortality is estimated at 30%.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.