ReviewJournal of neurology2010
How vital is sleep in Huntington's disease?
Review in Journal of neurology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- Sleep in Huntington's disease: a systematic review and meta-analysis of polysomongraphic findings.Sleep · 2019Pooled it
- Dysfunctions of sleep and the circadian rhythm in Huntington's disease.Frontiers in neurology · 2025Review
- Assessment of Fitbit Charge 4 for sleep stage and heart rate monitoring against polysomnography and during home monitoring in Huntington's disease.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- [Application of Polysomnography in Common Neurodegenerative Diseases].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023Review
- Ataxin2 functions via CrebA to mediate Huntingtin toxicity in circadian clock neurons.PLoS genetics · 2019Article
- Sleep Disorders in Huntington's Disease.Frontiers in psychiatry · 2019Review
- Physiological links of circadian clock and biological clock of aging.Protein & cell · 2017Review
- Circadian Rhythms, Sleep, and Disorders of Aging.Trends in endocrinology and metabolism: TEM · 2016Review
- Article
- Sleep Physiology Alterations Precede Plethoric Phenotypic Changes in R6/1 Huntington's Disease Mice.PloS one · 2015Article
- Circadian clocks and neurodegenerative diseases: time to aggregate?Current opinion in neurobiology · 2013Review
- Sleep and circadian dysfunction in neurodegenerative disorders: insights from a mouse model of Huntington's disease.Minerva pneumologica · 2012Article
- Circadian Abnormalities in Motor Activity in a BAC Transgenic Mouse Model of Huntington's Disease.PLoS currents · 2011Article
- Asymptomatic sleep abnormalities are a common early feature in patients with Huntington's disease.Current neurology and neuroscience reports · 2011Article
- Dysfunctions in circadian behavior and physiology in mouse models of Huntington's disease.Experimental neurology · 2011Article
- The Current Status of Neural Grafting in the Treatment of Huntington's Disease. A Review.Frontiers in integrative neuroscience · 2011Article
- Drosophila Models of Huntington's Disease exhibit sleep abnormalities.PLoS currents · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Huntington's disease (HD) is a fatal neurodegenerative disease caused by an abnormal expansion of a CAG repeat in exon 1 of the HD gene on chromosome 4. The disease runs a debilitating and progressive course with an average survival of 15-25 years after disease onset. HD patients classically develop involuntary movements including chorea, as well as progressive cognitive and psychiatric disturbances, although a number of other features have also been reported, including changes in sleep and circadian rhythms; it is this latter area that forms the focus of this review.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.