ArticlePloS one2010
Multi-locus sequence typing of a geographically and temporally diverse sample of the highly clonal human pathogen Bartonella quintana.
Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 40 citations in OpenAlex.
- Blood culture-negative endocarditis caused by Bartonella quintana in Iran.Scientific reports · 2024Article
- Genetic diversity of Bartonella species in small mammals in the Qinghai Menyuan section of Qilian Mountain National Park, China.Scientific reports · 2024Article
- Genomic properties of a Bartonella quintana strain from Japanese macaque (Macaca fuscata) revealed by genome comparison with human and rhesus macaque strains.Scientific reports · 2024Article
- Molecular epidemiology of Bartonella quintana endocarditis in patients from Israel and Eastern Africa.BMC infectious diseases · 2023Article
- Prevalence and diversity of small rodent-associated Bartonella species in Shangdang Basin, China.PLoS neglected tropical diseases · 2022Article
- Detection and genetic diversity of Bartonella species in small mammals from the central region of the Qinghai-Tibetan Plateau, China.Scientific reports · 2022Article
- Molecular detection and genetic characterization of small rodents associated Bartonella species in Zhongtiao Mountain, China.PloS one · 2022Article
- Genetic diversity of Bartonella species in small mammals in the Qaidam Basin, western China.Scientific reports · 2021Article
- Bartonella gene transfer agent: Evolution, function, and proposed role in host adaptation.Cellular microbiology · 2019Review
- Case Report:The American journal of tropical medicine and hygiene · 2019Review
- Multi-Locus Sequence Typing of Bartonella bacilliformis DNA Performed Directly from Blood of Patients with Oroya's Fever During a Peruvian Outbreak.PLoS neglected tropical diseases · 2016Article
- Japanese Macaques (Macaca fuscata) as Natural Reservoir of Bartonella quintana.Emerging infectious diseases · 2015Article
- Global multilocus sequence typing analysis of Mycoplasma bovis isolates reveals two main population clusters.Journal of clinical microbiology · 2015Article
- Classification of Bartonella strains associated with straw-colored fruit bats (Eidolon helvum) across Africa using a multi-locus sequence typing platform.PLoS neglected tropical diseases · 2015Article
- Molecular typing of "Candidatus Bartonella ancashi," a new human pathogen causing verruga peruana.Journal of clinical microbiology · 2013Article
- Multilocus sequence typing for characterization of Staphylococcus pseudintermedius.Journal of clinical microbiology · 2013Article
- Article
- Deciphering bartonella diversity, recombination, and host specificity in a rodent community.PloS one · 2013Article
- Reproductive clonality of pathogens: a perspective on pathogenic viruses, bacteria, fungi, and parasitic protozoa.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Bartonella quintana infections in captive monkeys, China.Emerging infectious diseases · 2011Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bartonella quintana is a re-emerging pathogen and the causative agent of a variety of disease manifestations in humans including trench fever. Various typing methods have been developed for B. quintana, but these tend to be limited by poor resolution and, in the case of gel-based methods, a lack of portability. Multilocus sequence typing (MLST) has been used to study the molecular epidemiology of a large number of pathogens, including B. henselae, a close relative of B. quintana. We developed a MLST scheme for B. quintana based on the 7 MLST loci employed for B. henselae with two additional loci to cover underrepresented regions of the B. quintana chromosome. A total of 16 B. quintana isolates spanning over 60 years and three continents were characterized. Allelic variation was detected in five of the nine loci. Although only 8/4270 (0.002%) of the nucleotide sites examined were variable over all loci, these polymorphisms resolved the 16 isolates into seven sequence types (STs). We also demonstrate that MLST can be applied on uncultured isolates by direct PCR from cardiac valve tissue, and suggest this method presents a promising approach for epidemiological studies in this highly clonal organism. Phylogenetic and clustering analyses suggest that two of the seven STs form a distinct lineage within the population.
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