Evidence map›Paper›PMID 20308743›Full record

ReviewThe Indian journal of medical research2010

Pathophysiology & genetics of obstructive sleep apnoea.

Lisa Campana, Danny J Eckert, Sanjay R Patel, Atul Malhotra

Abstract readReview
In one paragraph

Review in The Indian journal of medical research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 37 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
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  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lisa CampanaBrigham & Women's Hospital, Division of Sleep Medicine, Sleep Disorders Program & Harvard Medical School Boston, MA, USA.
Danny J Eckert
Sanjay R Patel
Atul Malhotra
Brigham and Women's Hospital · US

Funding

TRAINING IN SLEEP, CIRCADIAN &RESPIRATORY NEUROBIOLOGYT32HL007901 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Charles A Czeisler · 1998 to 2026
$18.5M
Single Motor Unit Genioglossus Recordings to Understand Sleep Apnea PathogenesisR01HL085188 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2008 to 2018
$3.5M
Mechanisms Underlying the Aging Predisposition to Obstructive Sleep ApneaR01HL090897 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MALHOTRA, ATUL · 2009 to 2012
$1.8M
Sleep Apnea and Obesity: Cardiovascular Risk AssessmentR01HL073146 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI MALHOTRA, ATUL · 2003 to 2008
$1.6M
Assessment of Upper Airway Mechanics Using Newer EMG TechniquesK24HL093218 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL · 2009 to 2013
$857k
The Genetics of Metabolic Dysfunction in Sleep ApneaK08HL081385 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI PATEL, SANJAY R · 2005 to 2009
$670k
NHLBI NIH HHS HL081385NHLBI NIH HHS K08 HL081385NHLBI NIH HHS K24 HL093218NHLBI NIH HHS P50 K24HL093218NHLBI NIH HHS R01 HL073146NHLBI NIH HHS R01 HL085188NHLBI NIH HHS R01-HL085188-01NHLBI NIH HHS R01 HL090897NHLBI NIH HHS R01HL090897NHLBI NIH HHS R01-HL73146NHLBI NIH HHS T32 HL007901
6 · The paper itself

Abstract

Obstructive sleep apnoea (OSA) is a highly prevalent condition with proven neurocognitive and cardiovascular consequences. OSA patients experience repetitive narrowing or collapse of the pharyngeal airway during sleep. Multiple factors likely underlie the pathophysiology of this condition with considerable inter-individual variation. Important risk factors for OSA include obesity, male gender, and ageing. However, the mechanisms underlying these major risk factors are not well understood. We briefly review the state-of-the-art knowledge regarding OSA pathogenesis in adults and highlight the potential role of genetics in influencing key OSA pathophysiological traits.

Indexed as

Biomechanical PhenomenaCardiovascular DiseasesHumansLungModels, BiologicalModels, GeneticRespirationRespiratory SystemRisk FactorsSleepSleep Apnea, ObstructiveTime Factors

Identifiers

PMID20308743
PMCPMC3858846
OpenAlexW2111274107

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.