Evidence map›Paper›PMID 20308644›Full record

ReviewArchives of internal medicine2010

Individualized medical decision making: necessary, achievable, but not yet attainable.

Liana Fraenkel, Terri R Fried

Open access · bronzeAbstract readReview
In one paragraph

Review in Archives of internal medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
20.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Guideline
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. Article
  9. Article
  10. Article
  11. Shared Decision Making: From Decision Science to Data Science.Medical decision making : an international journal of the Society for Medical Decision Making · 2020
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. End of life issues in the intensive care units.Medical journal, Armed Forces India · 2013
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Liana FraenkelDepartment of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA. liana.fraenkel@yale.edu
Terri R Fried
Yale University · US

Funding

Expanding Treatment Options for Older PersonsK24AG028443 · NIA · YALE UNIVERSITY · PI FRIED, TERRI R. · 2007 to 2011
$914k
Eliciting Patient Treatment Preferences for OsteoporosisK23AR048826 · NIAMS · YALE UNIVERSITY · PI FRAENKEL, LIANA · 2004 to 2008
$659k
NIAMS NIH HHS K23 AR048826NIA NIH HHS K24 AG028443NIA NIH HHS K24 AG28443
6 · The paper itself

Abstract

The need is urgent to provide older persons with individualized information about the benefits and harms of different diagnostic and treatment strategies. This need results from the growing recognition of the heterogeneity in outcomes in older persons with differing comorbidity profiles. The heterogeneity of benefits and harms resulting from treatment is not yet as well appreciated. Warfarin vs aspirin therapy for the reduction of stroke risk in nonvalvular atrial fibrillation provides an example of a treatment for which the benefit-to-harm ratio may actually reverse according to an older person's comorbidities, thus highlighting the importance of basing this treatment decision on individualized outcome data. Despite the wealth of studies in nonvalvular atrial fibrillation, many assumptions are necessary to calculate patient-specific outcomes, and these assumptions may lead to substantial overestimation or underestimation of benefits and harms. Improving care for patients with comorbidities will require substantive increases in the efforts and resources allocated to the collection and dissemination of outcome data for patients with varying comorbidities.

Indexed as

Decision MakingAtrial FibrillationFibrinolytic AgentsHumansRisk FactorsTreatment OutcomeFibrinolytic Agents

Identifiers

PMID20308644
PMCPMC2845319
OpenAlexW2087230523

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.