ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2010
Measurements of spontaneous rates of mutations in the recent past and the near future.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed.
- Measuring the change in deleterious mutation burden of barley germplasm conserved over one regeneration cycle.G3 (Bethesda, Md.) · 2026Article
- Clustering of inverted triplications in centromeric and subtelomeric chromosomal regions ofMicrobiology spectrum · 2026Article
- Genome-wide mapping of spontaneous DNA replication error-hotspots using mismatch repair proteins in rapidly proliferating Escherichia coli.Nucleic acids research · 2025Article
- What can we infer about mutation calling by using time-series mutation accumulation data and a Bayesian Mutation Finder?Ecology and evolution · 2024Article
- Deleterious and Adaptive Mutations in Plant Germplasm Conserved Ex Situ.Molecular biology and evolution · 2023Article
- The rate of de novo structural variation is increased in in vitro-produced offspring and preferentially affects the paternal genome.Genome research · 2023Article
- Very Low Rates of Spontaneous Gene Deletions and Gene Duplications in Dictyostelium discoideum.Journal of molecular evolution · 2023Article
- Characterization of nuclear DNA diversity in an individualFrontiers in plant science · 2023Article
- Phytochemical Compounds and Anticancer Activity ofCancers · 2022Article
- Is there still evolution in the human population?Biologia futura · 2022Review
- Comparative overview of emerging RNA viruses: Epidemiology, pathogenesis, diagnosis and current treatment.Annals of medicine and surgery (2012) · 2022Review
- Neural networks enable efficient and accurate simulation-based inference of evolutionary parameters from adaptation dynamics.PLoS biology · 2022Article
- Article
- Major population splits coincide with episodes of rapid climate change in a forest-dependent bird.Proceedings. Biological sciences · 2021Article
- A brief history and popularity of methods and tools used to estimate micro-evolutionary forces.Ecology and evolution · 2021Review
- Article
- Pedigree-based and phylogenetic methods support surprising patterns of mutation rate and spectrum in the gray mouse lemur.Heredity · 2021Article
- Genome-wide DNA mutations in Arabidopsis plants after multigenerational exposure to high temperatures.Genome biology · 2021Article
- The insertion of a mitochondrial selfish element into the nuclear genome and its consequences.Ecology and evolution · 2020Article
- Metabolic cost of rapid adaptation of single yeast cells.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
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2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The rate of spontaneous mutation in natural populations is a fundamental parameter for many evolutionary phenomena. Because the rate of mutation is generally low, most of what is currently known about mutation has been obtained through indirect, complex and imprecise methodological approaches. However, in the past few years genome-wide sequencing of closely related individuals has made it possible to estimate the rates of mutation directly at the level of the DNA, avoiding most of the problems associated with using indirect methods. Here, we review the methods used in the past with an emphasis on next generation sequencing, which may soon make the accurate measurement of spontaneous mutation rates a matter of routine.
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