Evidence map›Paper›PMID 20307839›Full record

ReviewThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2010

Human papillomavirus-related disease in men: not just a women's issue.

Joel M Palefsky

Erratum issuedOpen access · greenAbstract readReview
In one paragraph

Review in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 79 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 1 pooled it
15.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 1 synthesis or guideline pooled it, 230 citations in OpenAlex.

  1. Pooled it
  2. Anal Human Papillomavirus Infection Progression to Disease Among Men Who Have Sex With Men.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Trial
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  5. Article
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  9. The effects of human papillomavirus vaccination in Japan.Human vaccines & immunotherapeutics · 2025
    Article
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  13. Review
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19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Joel M PalefskyDepartment of Medicine, University of California, San Francisco, California 94143, USA. joel.Palefsky@ucsf.edu
University of California, San Francisco · US

Funding

Anal HPV Infection and ASIL in HIV+ and HIV- WomenR01CA088739 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PALEFSKY, JOEL MICHAEL · 2001 to 2006
$5.5M
NATURAL HISTORY OF ANAL NEOPLASIA IN HIV INFECTIONSR01CA054053 · NCI · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI PALEFSKY, JOEL · 1991 to 2002
$2.0M
NCI NIH HHS R01 CA054053NCI NIH HHS R01 CA088739
6 · The paper itself

Abstract

The most common cause of mortality related to human papillomavirus (HPV) infection is cervical cancer. However, male HPV infection is also an important concern, both for the disease burden in men and for the risk of transmission to women. HPV is associated with a variety of cancers in men, including anal cancer and a subset of penile and oral cancers. The incidence of anal and oral cancers related to HPV is increasing in the general population and is growing even faster among individuals who are immunocompromised because of human immunodeficiency virus (HIV) infection. Penile HPV infection is very common among heterosexual men and remains high throughout a wide range of ages. Likewise, anal HPV infection and anal intraepithelial neoplasia are very common throughout a wide range of ages in both HIV-negative and HIV-positive men who have sex with men. Other HPV-related diseases of clinical importance in men include condylomata acuminata (genital warts) and recurrent respiratory papillomatosis. The quadrivalent HPV vaccine has been shown to be highly efficacious in the prevention of genital warts in women and precancerous lesions of the cervix, vulva, and vagina. In addition, recent interim data have shown that the quadrivalent HPV vaccine is highly effective in reducing external genital lesions in young men. Although the protective efficacy of HPV vaccination in men has not yet been fully established-pending the outcome of public policy discussions and cost-efficacy studies-there may be a strong rationale for vaccinating boys, similar to girls, at an early age when they have had limited or no prior sexual activity.

Indexed as

Men's HealthAdolescentAdultAnus NeoplasmsCondylomata AcuminataHIV InfectionsHumansMaleMouth NeoplasmsPapillomavirus InfectionsPapillomavirus VaccinesPenile NeoplasmsRespiratory Tract InfectionsSexual BehaviorYoung AdultPapillomavirus Vaccines

Identifiers

PMID20307839
PMCPMC2871537
OpenAlexW1994074107

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.