Evidence map›Paper›PMID 20307503›Full record

ReviewBrain research2010

Regulatory RNAs in brain function and disorders.

Anna Iacoangeli, Riccardo Bianchi, Henri Tiedge

Abstract readReview
In one paragraph

Review in Brain research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Long noncoding RNAs and Alzheimer's disease.Clinical interventions in aging · 2016
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Anna IacoangeliThe Robert F. Furchgott Center for Neural and Behavioral Science, Department of Physiology and Pharmacology, State University of New York, Health Science Center at Brooklyn, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.
Riccardo Bianchi
Henri Tiedge
State University of New York · US

Funding

Translational Control in NeuronsR01NS046769 · NINDS · SUNY DOWNSTATE MEDICAL CENTER · PI TIEDGE, HENRI · 2003 to 2019
$4.8M
Small RNAs in NeuronsR01DA026110 · NIDA · SUNY DOWNSTATE MEDICAL CENTER · PI TIEDGE, HENRI · 2009 to 2017
$2.8M
NIDA NIH HHS DA026110NIDA NIH HHS R01 DA026110NINDS NIH HHS NS046769NINDS NIH HHS R01 NS046769
6 · The paper itself

Abstract

Regulatory RNAs are being increasingly investigated in neurons, and important roles in brain function have been revealed. Regulatory RNAs are non-protein-coding RNAs (npcRNAs) that comprise a heterogeneous group of molecules, varying in size and mechanism of action. Regulatory RNAs often exert post-transcriptional control of gene expression, resulting in gene silencing or gene expression stimulation. Here, we review evidence that regulatory RNAs are implicated in neuronal development, differentiation, and plasticity. We will also discuss npcRNA dysregulation that may be involved in pathological states of the brain such as neurodevelopmental disorders, neurodegeneration, and epilepsy.

Indexed as

AnimalsBrainBrain DiseasesGene Expression RegulationHumansRNA, UntranslatedRNA, Untranslated

Identifiers

PMID20307503
PMCPMC3524968
OpenAlexW2074912199

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.