Evidence map›Paper›PMID 20306512›Full record

ReviewIUBMB life2010

From stem cell to erythroblast: regulation of red cell production at multiple levels by multiple hormones.

Harvey Lodish, Johan Flygare, Song Chou

Abstract readReview
In one paragraph

Review in IUBMB life, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Harvey LodishWhitehead Institute for Biomedical Research, Cambridge, MA 02142, USA. lodish@wi.mit.edu
Johan Flygare
Song Chou

Funding

TRANSCRIPTION FACTOR GATA-1 IN TERMINAL ERYTHROID DEVELOPMENTP01HL032262 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI ORKIN, STUART H · 1985 to 2021
$38.9M
Growth factors and engineered stroma for HSC expansionR01DK067356 · NIDDK · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI LODISH, HARVEY F · 2004 to 2010
$2.4M
NHLBI NIH HHS P01 HL032262NHLBI NIH HHS P01 HL 32262NIDDK NIH HHS DK067356NIDDK NIH HHS R01 DK067356
6 · The paper itself

Abstract

This article reviews the regulation of production of red blood cells at several levels: (1) the ability of erythropoietin and adhesion to a fibronectin matrix to stimulate the rapid production of red cells by inducing terminal proliferation and differentiation of committed erythroid CFU-E progenitors; (2) the regulated expansion of the pool of earlier BFU-E erythroid progenitors by glucocorticoids and other factors that occurs during chronic anemia or inflammation; and (3) the expansion of thehematopoietic cell pool to produce more progenitors of all hematopoietic lineages.

Indexed as

ErythropoiesisAnimalsCell DifferentiationCell ProliferationErythroblastsErythroid Precursor CellsErythropoietinGlucocorticoidsHematopoietic Stem CellsHumansStem Cell FactorErythropoietinGlucocorticoidsStem Cell Factor

Identifiers

PMID20306512
PMCPMC2893266

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.