Evidence map›Paper›PMID 20305826›Full record

ReviewExpert review of respiratory medicine2010

Role of infection in the development and exacerbation of asthma.

Theresa W Guilbert, Loren C Denlinger

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of respiratory medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 91 citations in OpenAlex.

  1. Article
  2. Review
  3. Observational
  4. Article
  5. Review
  6. Review
  7. Asthma-associated bacterial infections: Are they protective or deleterious?The journal of allergy and clinical immunology. Global · 2023
    Review
  8. Article
  9. Article
  10. Review
  11. Shifts in Asthma Evaluation and Management During COVID-19.Current treatment options in allergy · 2022
    Review
  12. [Influenza and cardiorespiratory events: a clinical-epidemiological review with a multidisciplinary point of view].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2021
    Review
  13. Article
  14. Observational
  15. Article
  16. Article
  17. Association ofExperimental and therapeutic medicine · 2017
    Article
  18. Article
  19. The Regulatory Function of Eosinophils.Microbiology spectrum · 2016
    Review
  20. Macrolides for Acute Wheezing Episodes in Preschool Children.Pediatric allergy, immunology, and pulmonology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Theresa W GuilbertDepartment of Pediatrics, University of Wisconsin School of Medicine & Public Health, 600 Highland Avenue, K4/944, CSC-4108, Madison, WI 53792, USA. tguilbert@wisc.edu
Loren C Denlinger
University of Wisconsin–Madison · US

Funding

Virus-Bacterial Interactions and Exacerba of AsthmaP01HL070831 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI GANGNON, RONALD E · 2002 to 2017
$31.3M
Thr Role of Pin1 in AirwayP01HL088594 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI JARJOUR, NIZAR N · 2008 to 2017
$21.0M
CHILDHOOD ASTHMA: INITIATION AND INTERVENTIONU10HL064305 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI LEMANSKE, ROBERT F · 1999 to 2008
$5.8M
Variant Nucleotide Receptor Function in Airway DisordersK23HL081492 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI DENLINGER, LOREN C · 2008 to 2010
$428k
NHLBI NIH HHS K23 HL081492NHLBI NIH HHS P01 HL070831NHLBI NIH HHS P01 HL088594NHLBI NIH HHS U10 HL064305
6 · The paper itself

Abstract

Respiratory infections are associated with wheezing illnesses in all ages and may also impact the development and severity of asthma. Respiratory tract infections caused by viruses, Chlamydophila or Mycoplasma have been hypothesized to have significant roles in the pathogenesis of asthma. Progress is being made toward establishing the mechanisms by which these agents can cause acute wheezing and impact the pathophysiology of asthma. Host factors probably contribute to the risk of asthma inception and exacerbation, and these contributions may also vary with respect to early- versus adult-onset disease. This review discusses these various associations as they pertain to the development and exacerbation of asthma.

Indexed as

AsthmaAcute DiseaseChlamydophila InfectionsChronic DiseaseHumansMycoplasma InfectionsRespiratory SoundsRespiratory Tract InfectionsRisk FactorsVirus Diseasesasthmaasthma inceptionexacerbationrespiratory infectionvirus

Identifiers

PMID20305826
PMCPMC2840256
OpenAlexW1967864815

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.