Evidence map›Paper›PMID 20305774›Full record

ReviewDeutsches Arzteblatt international2010

The epidemiology, etiology, diagnosis, and treatment of osteoarthritis of the knee.

Joern W-P Michael, Klaus U Schlüter-Brust, Peer Eysel

Erratum issued 5 registry-linked trialsOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Deutsches Arzteblatt international, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 5 registered trials, which are not on this map. Cited by 347 papers, 17 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
347citing papers in PubMed, 17 pooled it
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04061733 naunknown statusnot on this mapstarted 2019, after this paper: background citation

New Hydroxyethyl Cellulose Hydrogel for the Treatment of the Pain of Knee Arthrosis

TypeinterventionalSponsorPromedonRan2019 to 2024Enrolled50ConditionsOsteoarthritis, Knee, PainArmsHydrogel injection
NCT06003413 completednot on this mapstarted 2023, after this paper: background citation

Evaluation of the Relationship Between the Architecture of the Quadriceps, Tibialis Anterior and Gastrocnemius Muscles and Muscle Strength in Female Gonarthrosis Patients

TypeobservationalSponsorBezmialem Vakif UniversityRan2023 to 2024Enrolled30ConditionsOsteo Arthritis Knee, Gonarthrosis, Osteoarthritis
NCT06460662 nacompletednot on this mapstarted 2024, after this paper: background citation

Effects of Agility and Perturbation Based Training in Addition to Routine Physical Therapy on Pain, Function and Quality of Life in Patients With Knee Osteoarthritis

TypeinterventionalSponsorRiphah International UniversityRan2024 to 2024Enrolled26ConditionsKnee OsteoarthritisArmsRoutine Physical Therapy
NCT06914960 narecruitingnot on this mapstarted 2025, after this paper: background citation

Ultrasound-Guided Genicular Nerve Radiofrequency Ablation Therapy: Effectiveness of 5 Nerve Protocols Versus 3 Nerve and 2 Nerve Protocols - A Prospective Randomized Controlled Study

TypeinterventionalSponsorBengu TuremenogullariRan2025 to 2026Enrolled66ConditionsGonarthrosisArms2-point Radiofrequency Ablation, 3-point Radiofrequency Ablation, 5-point Radiofrequency Ablation
NCT07141316 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Effects of Blood Flow Restriction Combined With Electrostimulation After Knee Arthroplasty: Randomized Controlled Trial

TypeinterventionalSponsorUniversity of PaviaRan2025 to 2026Enrolled60ConditionsOsteo Arthritis KneeArmsBlood flow restriction combined with electrostimulation.
3 · Its place in the literature

Who cites it

347 citing papers in PubMed, 17 syntheses or guidelines pooled it, 769 citations in OpenAlex.

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287 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joern W-P MichaelKlinik und Poliklinik für Orthopädie und Unfallchirurgie, Universität Köln, Köln, Germany. joern.michael@uk-koeln.de
Klaus U Schlüter-Brust
Peer Eysel
Klinik und Poliklinik für Psychosomatik und Psychotherapie · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteoarthritis is the most common joint disease of adults worldwide. Its incidence rises with age. Both intrinsic and extrinsic risk factors promote its development. In men aged 60 to 64, the right knee is more commonly affected; in women, the right and left knees are affected with nearly equal frequency.

methodsThe PubMed, Medline, Embase and Cochrane Library databases were selectively searched for current studies (up to September 2009; case reports excluded) on the epidemiology, etiology, diagnosis, staging, and treatment of osteoarthritis of the knee. The search terms were "gonarthrosis," "prevention," "conservative treatment," "joint preservation," "physical activity," "arthroscopy," "osteotomy," "braces," "orthoses," and "osteoarthritis knee joint." RESULTS AND

conclusionOsteoarthritis is not yet a curable disease, and its pathogenesis remains unclear. The best treatment for osteoarthritis of the knee is prevention. The goal of therapy is to alleviate clinical manifestations. The therapeutic spectrum ranges from physiotherapy and orthopedic aids to pharmacotherapy and surgery.

Indexed as

Osteoarthritis, KneePhysical Therapy ModalitiesAntirheumatic AgentsArthroplastyHumansUnited StatesAntirheumatic Agents

Identifiers

PMID20305774
PMCPMC2841860
OpenAlexW2133075927

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.