ArticleJournal of fluid mechanics2010
Effect of a soluble surfactant on a finite sized bubble motion in a blood vessel.
Article in Journal of fluid mechanics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 24 citations in OpenAlex.
- Circulating Bubbles in Decompression Sickness: Pathophysiology and Experimental Models.Biomolecules · 2026Review
- Surfactant reduction of cerebral infarct size and behavioral deficit in a rat model of cerebrovascular arterial gas embolism.Journal of applied physiology (Bethesda, Md. : 1985) · 2013Article
- Computational simulation of hematocrit effects on arterial gas embolism dynamics.Aviation, space, and environmental medicine · 2012Article
- Mechanotransductional basis of endothelial cell response to intravascular bubbles.Integrative biology : quantitative biosciences from nano to macro · 2011Article
- Generalized Langevin dynamics of a nanoparticle using a finite element approach: thermostating with correlated noise.The Journal of chemical physics · 2011Article
- Surfactant properties differentially influence intravascular gas embolism mechanics.Annals of biomedical engineering · 2010Article
- In vitro surfactant mitigation of gas bubble contact-induced endothelial cell death.Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, IncArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
We present detailed results for the motion of a finite sized gas bubble in a blood vessel. The bubble (dispersed phase) size is taken to be such as to nearly occlude the vessel. The bulk medium is treated as a shear thinning Casson fluid and contains a soluble surfactant that adsorbs and desorbs from the interface. Three different vessel sizes, corresponding to a small artery, a large arteriole, and a small arteriole, in normal humans, are considered. The hematocrit (volume fraction of RBCs) has been taken to be 0.45. For arteriolar flow, where relevant, the Fahraeus-Lindqvist effect is taken into account. Bubble motion cause temporal and spatial gradients of shear stress at the cell surface lining the vessel wall as the bubble approaches the cell, moves over it and passes it by. Rapid reversals occur in the sign of the shear stress imparted to the cell surface during this motion. Shear stress gradients together with sign reversals are associated with a recirculation vortex at the rear of the moving bubble. The presence of the surfactant reduces the level of the shear stress gradients imparted to the cell surface as compared to an equivalent surfactant-free system. Our numerical results for bubble shapes and wall shear stresses may help explain phenomena observed in experimental studies related to gas embolism, a significant problem in cardiac surgery and decompression sickness.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.