ArticleNature methods2010
Direct determination of molecular haplotypes by chromosome microdissection.
Article in Nature methods, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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Who cites it
50 citing papers in PubMed.
- Phased Genome Assemblies.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Experimental method for haplotype phasing across the entire length of chromosome 21 in trisomy 21 cells using a chromosome elimination technique.Journal of human genetics · 2022Article
- Article
- Isolation and sequencing of a single copy of an introgressed chromosome from a complex genome for gene and SNP identification.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Cataloguing experimentally confirmed 80.7 kb-long ACKR1 haplotypes from the 1000 Genomes Project database.BMC bioinformatics · 2021Article
- Determination of complete chromosomal haplotypes by bulk DNA sequencing.Genome biology · 2021Article
- Inference of Chromosome-Length Haplotypes Using Genomic Data of Three or a Few More Single Gametes.Molecular biology and evolution · 2020Article
- Article
- Efficient and unique cobarcoding of second-generation sequencing reads from long DNA molecules enabling cost-effective and accurate sequencing, haplotyping, and de novo assembly.Genome research · 2019Article
- Long range haplotyping of paired-homologous chromosomes by single-chromosome sequencing of a single cell.Scientific reports · 2018Article
- 3C-PCR: a novel proximity ligation-based approach to phase chromosomal rearrangement breakpoints with distal allelic variants.Human genetics · 2018Article
- Dense and accurate whole-chromosome haplotyping of individual genomes.Nature communications · 2017Article
- Recent Advances in Experimental Whole Genome Haplotyping Methods.International journal of molecular sciences · 2017Review
- Hotspot Selective Preference of the Chimeric Sequences Formed in Multiple Displacement Amplification.International journal of molecular sciences · 2017Article
- Chromosome-Range Whole-Genome High-Throughput Experimental Haplotyping by Single-Chromosome Microdissection.Methods in molecular biology (Clifton, N.J.) · 2017Article
- Direct chromosome-length haplotyping by single-cell sequencing.Genome research · 2016Article
- The second decade of 3C technologies: detailed insights into nuclear organization.Genes & development · 2016Review
- GenomeLaser: fast and accurate haplotyping from pedigree genotypes.Bioinformatics (Oxford, England) · 2015Article
- Article
- References for Haplotype Imputation in the Big Data Era.Molecular biology (Los Angeles, Calif.) · 2015Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Direct observation of haplotypes is still technically challenging. Here we report a method for the determination of haplotypes through chromosome microdissection. We determined human long-range chromosomal haplotypes with more than 98.85% accuracy at 24,245 genome-wide heterozygous single-nucleotide polymorphism (SNP) loci.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.