Evidence map›Paper›PMID 20303869›Full record

ArticleCell2010

Autoinflammatory disease reloaded: a clinical perspective.

Daniel L Kastner, Ivona Aksentijevich, Raphaela Goldbach-Mansky

Abstract read
In one paragraph

Article in Cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 203 papers.

0numbers the graph read from it
0cells of the map it votes in
203citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

203 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Nature-inspired IL-1 targeted therapy to treat chronic inflammatory diseases.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  5. Article
  6. Article
  7. Observational
  8. Constraints and tunability of antigen-agnostic memory durability.bioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article

143 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daniel L KastnerLaboratory of Clinical Investigation, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA. kastnerd@mail.nih.gov
Ivona Aksentijevich
Raphaela Goldbach-Mansky

Funding

Clinical Support Services for the NIAMS Intramural Research ProgramZIDAR041180 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI COLBERT, ROBERT · 2009 to 2025
$119.2M
Clinical Training in RheumatologyZIEAR041176 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI COLBERT, ROBERT · 2009 to 2025
$29.8M
Outcomes in Rheumatic DiseasesZIAAR041153 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI WARD, MICHAEL · 2009 to 2020
$12.6M
Studies of the Natural History of Rheumatic DiseasesZIAAR041170 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI HASNI, SARFARAZ · 2009 to 2025
$11.1M
Pathogenesis and treatment studies in patients with NOMID and related diseasesZIAAR041138 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI GOLDBACH-MANSKY, RAPHAELA · 2009 to 2016
$8.6M
Clinical Support Services for the NIAMS Intramural Research ProgramZ01AR041180 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI KASTNER, DANIEL · 2008 to 2008
$3.4M
Genetics Of Familial Mediterranean Fever/ Related ConditZ01AR041083 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI KASTNER, DANIEL L · 1990 to 2008
$3.3M
Genetics, Natural History, and Pathophysiology of Behcet's DiseaseZIAAR041162 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI KASTNER, DANIEL · 2009 to 2010
$3.0M
Genetic Analysis of Complex Inflammatory DisordersZ01AR041139 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI KASTNER, DANIEL L · 2003 to 2008
$2.8M
GENETICS OF THE DOMINANTLY INHERITED PERIODIC FEVER SYNDROMESZ01AR041123 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI KASTNER, DANIEL L · 1999 to 2008
$2.8M
Genetics Of Familial Mediterranean Fever and Related ConditionsZIAAR041083 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI KASTNER, DANIEL · 2009 to 2010
$2.4M
Pathogenesis and treatment studies in patients with NOMID and related diseasesZ01AR041138 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI GOLDBACH-MANSKY, RAPHAELA · 2003 to 2008
$2.3M
Intramural NIH HHS Z01 AR041083Intramural NIH HHS Z01 AR041123Intramural NIH HHS Z01 AR041138Intramural NIH HHS Z01 AR041139Intramural NIH HHS Z01 AR041153Intramural NIH HHS Z01 AR041170Intramural NIH HHS Z01 AR041176Intramural NIH HHS Z01 AR041180Intramural NIH HHS Z99 AA999999Intramural NIH HHS Z99 AR999999Intramural NIH HHS Z99 DA999999Intramural NIH HHS ZIA AR041083Intramural NIH HHS ZIA AR041123Intramural NIH HHS ZIA AR041138Intramural NIH HHS ZIA AR041139Intramural NIH HHS ZIA AR041153Intramural NIH HHS ZIA AR041162Intramural NIH HHS ZIA AR041170Intramural NIH HHS ZIA AR041185Intramural NIH HHS ZID AR041180Intramural NIH HHS ZIE AR041176
6 · The paper itself

Abstract

Our understanding of the etiology of autoinflammatory disease is growing rapidly. Recent advances offer new opportunities for therapeutic intervention and suggest that the definition of what constitutes an autoinflammatory disease should be reassessed.

Indexed as

AnimalsAutoantibodiesAutoimmune DiseasesCytokinesHereditary Autoinflammatory DiseasesHumansAutoantibodiesCytokines

Identifiers

PMID20303869
PMCPMC3541025

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.