Evidence map›Paper›PMID 20303726›Full record

ReviewCurrent opinion in cell biology2010

Down the rabbit hole of centromere assembly and dynamics.

Yamini Dalal, Minh Bui

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. The CENP-A nucleosome: a dynamic structure and role at the centromere.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2012
    Review
  7. Tripartite organization of centromeric chromatin in budding yeast.Proceedings of the National Academy of Sciences of the United States of America · 2012
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Kinetochore assembly: if you build it, they will come.Current opinion in cell biology · 2011
    Review
  14. Tetrameric organization of vertebrate centromeric nucleosomes.Proceedings of the National Academy of Sciences of the United States of America · 2010
    Article
  15. Article
  16. Review
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yamini DalalChromatin Structure and Epigenetic Mechanisms Unit, Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, NIH, Bethesda, MD 20892, USA. dalaly@mail.nih.gov
Minh Bui
National Cancer Institute · US

Funding

Biomechanical properties of chromatin in cancer and normal cellsZIABC011207 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI DALAL, YAMINI P · 2009 to 2025
$8.8M
Kinetochore Interaction with Centromere Chromatin in human cellsZIABC011209 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI DALAL, YAMINI P · 2009 to 2025
$5.5M
Intramural NIH HHS ZIA BC011207
6 · The paper itself

Abstract

The centromere is perhaps the most iconic feature on a eukaryotic chromosome. An amateur enthusiast equipped with a light microscope can easily identify the center of each metacentric chromosome, marking the spot responsible for accurate genome segregation. This review will highlight findings that provide novel insights into how centromeres are assembled and disassembled, the role centromeric proteins play in repair, epigenetic features uniquely found at the centromere, and the three dimensional organization of centromeres caught in the act of mitosis. These advances have unveiled a veritable wonderland of non-canonical features that drive centromere function.

Indexed as

AnimalsCentromereChromosomal Proteins, Non-HistoneHumansInterphaseKinetochoresMitosisNucleosomesChromosomal Proteins, Non-HistoneNucleosomes

Identifiers

PMID20303726
PMCPMC2989927
OpenAlexW2041846316

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.