Evidence map›Paper›PMID 20303404›Full record

ReviewExperimental gerontology2010

Preservation of eccentric strength in older adults: Evidence, mechanisms and implications for training and rehabilitation.

Marc Roig, Donna L Macintyre, Janice J Eng, Marco V Narici, Constantinos N Maganaris, W Darlene Reid

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Experimental gerontology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 53 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 3 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04099316 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Effects of Eccentric-based Training on Muscle Strength and Physical Function in Older Adults

TypeinterventionalSponsorSeoul National University Bundang HospitalRan2017 to 2019Enrolled27ConditionsSarcopeniaArmsEccentric exercise, Conventional resistance exercise
NCT04600050 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Effect of Eccentric Contraction-based Resistance Exercise on Functional Recovery in Chronic Stroke Patients

TypeinterventionalSponsorSeoul National University Bundang HospitalRan2020 to 2021Enrolled40ConditionsStrokeArmsusual care and exercise education, Eccentric exercise
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 3 syntheses or guidelines pooled it, 145 citations in OpenAlex.

  1. Pooled it
  2. Chronic Adaptations to Eccentric Cycling Training: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023
    Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Article
  11. Using Isometric Squat Strength to Predict Concentric and Eccentric Squat Strength in Young and Older Adults.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Eccentric Exercise: Adaptations and Applications for Health and Performance.Journal of functional morphology and kinesiology · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Marc RoigDepartment of Physical Therapy, University of British Columbia, Vancouver, Canada. markredj@interchange.ubc.ca
Donna L Macintyre
Janice J Eng
Marco V Narici
Constantinos N Maganaris
W Darlene Reid
University of British Columbia · CAManchester Metropolitan University · GBGF Strong Rehabilitation Centre · CA

Funding

CIHR 63617
6 · The paper itself

Abstract

Overall reductions in muscle strength typically accompany the aging process. However, older adults show a relatively preserved capacity of producing eccentric strength. The preservation of eccentric strength in older adults is a well-established phenomenon, occurring indiscriminately across different muscle groups, independent of age-related architectural changes in muscle structure and velocity of movement. The mechanisms for the preservation of eccentric strength appear to be mechanical and cellular in origin and include both passive and active elements regulating muscle stiffness. The age-related accumulation of non-contractile material in the muscle-tendon unit increases passive stiffness, which might offer mechanical advantage during eccentric contractions. In addition, the preserved muscle tension and increased instantaneous stiffness of old muscle fibers during stretch increase active stiffness, which might enhance eccentric strength. The fact that the preservation of eccentric strength is present in people with chronic conditions when compared to age-matched healthy controls indicates that the aging process per se does not exclusively mediate the preservation of eccentric strength. Physical inactivity, which is common in elderly and people with chronic conditions, is a potential factor regulating the preservation of eccentric strength. When compared to concentric strength, the magnitude of preservation of eccentric strength in older adults ranges from 2% to 48% with a mean value of 21.6% from all studies. This functional reserve of eccentric strength might be clinically relevant, especially to initiate resistance training and rehabilitation programs in individuals with low levels of strength.

Indexed as

AgedAged, 80 and overAgingFemaleHumansMaleMuscle ContractionMuscle Fibers, SkeletalMuscle StrengthSarcopenia

Identifiers

PMID20303404
PMCPMC3326066
OpenAlexW2022204551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.