Evidence map›Paper›PMID 20303035›Full record

ReviewTransfusion medicine reviews2010

Is there a role for autologous/placental red blood cell transfusions in the anemia of prematurity?

Ronald G Strauss, John A Widness

Registry-linked trialAbstract readEvaluation StudyReview
In one paragraph

Review in Transfusion medicine reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05612919 (Safety, Feasibility and Efficacy of Red Blood Cells From Umbilical Cord Blood for Transfusion of Extremely Preterm Infants), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05612919 nacompletednot on this mapstarted 2023, after this paper: background citation

Safety, Feasibility and Efficacy of Red Blood Cells From Umbilical Cord Blood for Transfusion of Extremely Preterm Infants: Clinical Phase

TypeinterventionalSponsorHospital Clinic of BarcelonaRan2023 to 2025Enrolled41ConditionsInfant, Extremely Premature, Erythrocyte Transfusion, Umbilical Cord IssueArmsRed blood cell from umbilical cord blood, Red blood cell from adult donor
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. New frontiers in neonatal red blood cell transfusion research.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Review
  4. Observational
  5. Haemoglobin Levels in Early Life among Infants with and without Retinopathy of Prematurity.International journal of environmental research and public health · 2021
    Article
  6. Article
  7. Review
  8. Prevention of the anaemia of prematurity.International journal of pediatrics & adolescent medicine
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Ronald G StraussDepartment of Pathology, University of Iowa College of Medicine, Iowa City, IA 52242, USA. ronald-strauss@uiowa.edu
John A Widness

Funding

THE RoLE OF NEONATAL ANEMIA IN LEARNING AND MEMORYP01HL046925 · NHLBI · UNIVERSITY OF IOWA · PI JOSEPHSON, CASSANDRA D · 1992 to 2022
$34.3M
UNIVERSITY OF IOWA CTSA FOR PEDIATRIC RESEARCHUL1RR024979 · NCRR · UNIVERSITY OF IOWA · PI ROSENTHAL, GARY E · 2007 to 2011
$31.8M
NCRR NIH HHS UL1 RR024979NHLBI NIH HHS P01 HL046925
6 · The paper itself

Abstract

Because most extremely preterm infants with birth weight less than 1000 g need red blood cell transfusions, many attempts have been made to collect, process, and store placental blood (ie, umbilical cord blood) for autologous transfusions. Although it is feasible to do this, multiple problems in doing so including insufficient volumes collected, clotting, hemolysis, bacterial contamination, failure to significantly supplant need for allogeneic transfusions, and high costs have led many to question whether, on balance, autologous/placental red blood cell transfusion offers clinically significant benefits.

Indexed as

Anemia, NeonatalBlood Transfusion, AutologousErythrocyte TransfusionFemaleFetal BloodHealth Services Needs and DemandHumansInfant, NewbornPlacental CirculationPregnancy

Identifiers

PMID20303035
PMCPMC2862623

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.