Evidence map›Paper›PMID 20300907›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2010

Relation of left-ventricular dyssynchrony by phase analysis of gated SPECT images and cardiovascular events in patients with implantable cardiac defibrillators.

Wael A Aljaroudi, Fadi G Hage, Daniel Hermann, Harish Doppalapudi, Rajesh Venkataraman, Jaekyeong Heo, Ami E Iskandrian

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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Safety of regadenoson in patients with end-stage liver disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2011
    Trial
  4. Left ventricular mechanical dyssnchrony: A potential new marker for 3-vessel CAD.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  5. Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2022: single photon emission computed tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Review
  6. Left ventricular mechanical dyssynchrony in patient with CAD: The Saga continues.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  7. Are SPECT MPI measures of dyssynchrony dyssynchronous?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  8. Left ventricular regional asynchrony: Earliest marker for ischemic cardiomyopathy?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  9. A perfect tool for comprehensive evaluation of myocardial perfusion and function: Stress PET imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  10. Dyssynchrony as a marker of adverse prognosis among patients with coronary artery disease and heart failure.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  11. The prognostic value of diastolic and systolic mechanical left ventricular dyssynchrony among patients with coronary artery disease and heart failure.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  12. Article
  13. Could myocardial viability be related to left ventricular dyssynchrony? Simultaneous evaluation by gated SPECT-MPI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  14. Left ventricular mechanical dyssynchrony assessment in long-standing type II diabetes mellitus patients with normal gated SPECT-MPI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Observational
  15. Interactions between myocardial sympathetic denervation and left ventricular mechanical dyssynchrony: A CZT analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  16. Mechanical dyssynchrony with phase analysis of gated SPECT: Nap time is over.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  17. Left ventricular mechanical dyssynchrony graduation of myocardial perfusion gated SPECT phase analysis: What next.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  18. Mechanical dyssynchrony according to validated cut-off values using gated SPECT myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  19. Detection of interventricular dyssynchrony: An evolution of the phase analysis technique.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  20. Impact of cardiac reverse remodeling after cardiac resynchronization therapy assessed by myocardial perfusion imaging on ventricular arrhythmia.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Wael A AljaroudiDivision of Cardiovascular Diseases, Department of Medicine, University of Alabama at Birmingham, 318 LHRB, 1900 University BLVD, Birmingham, AL 35294-0006, USA. wjaroudi@hotmail.com
Fadi G Hage
Daniel Hermann
Harish Doppalapudi
Rajesh Venkataraman
Jaekyeong Heo
Ami E Iskandrian

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft-ventricular (LV) dyssynchrony could be measured by gated SPECT myocardial perfusion imaging (MPI). This study examined the relation between the degree of dyssynchrony and outcome in patients with implantable cardiac defibrillators (ICDs). METHODS AND

resultsWe studied 70 patients with ICD and LV ejection fraction (EF) <.40 by gated MPI (performed within 6 weeks of the device implantation). The images were re-processed using phase analysis to derive phase standard deviation (SD) and histogram bandwidth. All-cause mortality and appropriate ICD shocks were identified as the primary endpoint. There were 87% men, aged 62 +/- 11 years. The EF was 26 +/- 8% (range 12%-39%). The phase SD was 51 degrees +/- 20 degrees (range 12 degrees -99 degrees ) and the histogram bandwidth was 157 degrees +/- 72 degrees (range 21 degrees -327 degrees ). The SD and bandwidth were significantly greater than corresponding values in patients with normal EF (15.8 +/- 11.8 degrees and 42.0 +/- 28.4 degrees , respectively, P < .0001, each). At 1 year, 8 patients (11%) died or had shocks. The patients with events had higher phase SD than those without events (60 +/- 5 degrees vs 50 +/- 21 degrees , P = .002). The histogram bandwidth was also higher in those with events (185 +/- 37 vs 154 +/- 75, P = .07). All patients with event had a phase SD >or= 50 degrees , while none of the patients with a phase SD < 50 degrees (N = 26) had an event (P = .02).

conclusionsThe severity of LV dyssynchrony by phase analysis in patients with LV dysfunction, and ICD is associated with increased risk of death and appropriate ICD shock; a phase SD < 50 degrees was associated with no events at 1 year.

Indexed as

Cardiac-Gated Single-Photon Emission Computer-Assisted TomographyDefibrillators, ImplantableMyocardial Perfusion ImagingAgedFemaleHumansMaleMiddle AgedVentricular Dysfunction, Left

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.