Evidence map›Paper›PMID 20300577›Full record

ArticleInterdisciplinary perspectives on infectious diseases2010

Enteroaggregative Escherichia coli: An Emerging Enteric Food Borne Pathogen.

P Kaur, A Chakraborti, A Asea

Open access · goldAbstract read
In one paragraph

Article in Interdisciplinary perspectives on infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 116 citations in OpenAlex.

  1. Review
  2. EnteroaggregativeEcoSal Plus · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Antimicrobial Resistance in DiverseAntibiotics (Basel, Switzerland) · 2024
    Review
  7. Article
  8. Article
  9. A Mini-Review of EnteroaggregativePolish journal of microbiology · 2023
    Review
  10. Article
  11. Prevalence of DiarrhoeagenicMicroorganisms · 2023
    Article
  12. Article
  13. Evaluation of the frequency ofIranian journal of microbiology · 2022
    Article
  14. Article
  15. Genomic comparisons ofMicrobial genomics · 2021
    Article
  16. Comparative Pathogenomics ofInfection and immunity · 2021
    Article
  17. Article
  18. Article
  19. DETECTION OF DIARRHEAGENICAfrican journal of infectious diseases · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

P KaurDepartment of Pathology, Scott & White Memorial Hospital and Clinic, The Texas A&M Health Science Center College of Medicine, Temple, TX 76508, USA.
A Chakraborti
A Asea
Post Graduate Institute of Medical Education and Research · INTexas A&M Health Science Center · US

Funding

Circulating HSP70 in Hyperthermia and Cancer TherapyR01CA091889 · NCI · SCOTT AND WHITE MEMORIAL HOSPITAL · PI ASEA, ALEXZANDER A · 2003 to 2006
$1.3M
NCI NIH HHS R01 CA091889
6 · The paper itself

Abstract

Enteroaggregative Escherichia coli (EAEC) are quite heterogeneous category of an emerging enteric pathogen associated with cases of acute or persistent diarrhea worldwide in children and adults, and over the past decade has received increasing attention as a cause of watery diarrhea, which is often persistent. EAEC infection is an important cause of diarrhea in outbreak and non-outbreak settings in developing and developed countries. Recently, EAEC has been implicated in the development of irritable bowel syndrome, but this remains to be confirmed. EAEC is defined as a diarrheal pathogen based on its characteristic aggregative adherence (AA) to HEp-2 cells in culture and its biofilm formation on the intestinal mucosa with a "stacked-brick" adherence phenotype, which is related to the presence of a 60 MDa plasmid (pAA). At the molecular level, strains demonstrating the aggregative phenotype are quite heterogeneous; several virulence factors are detected by polymerase chain reaction; however, none exhibited 100% specificity. Although several studies have identified specific virulence factor(s) unique to EAEC, the mechanism by which EAEC exerts its pathogenesis is, thus, far unknown. The present review updates the current knowledge on the epidemiology, chronic complications, detection, virulence factors, and treatment of EAEC, an emerging enteric food borne pathogen.

Identifiers

PMID20300577
PMCPMC2837894
OpenAlexW1994759640

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.