Evidence map›Paper›PMID 20300210›Full record

ReviewCold Spring Harbor perspectives in biology2010

Motor axon pathfinding.

Dario Bonanomi, Samuel L Pfaff

Abstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
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  10. Netrin-1 as A neural guidance protein in development and reinnervation of the larynx.Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft · 2024
    Review
  11. Article
  12. Article
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  19. Article
  20. Three-dimensionalNeural regeneration research · 2022
    Review

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dario BonanomiGene Expression Laboratory, The Salk Institute for Biological Studies, La Jolla, California 92037, USA.
Samuel L Pfaff

Funding

Genetic Control of Motor Neuron Development and FunctionR37NS037116 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI PFAFF, SAMUEL L. · 2007 to 2013
$3.6M
Proto-oncogenes in Axon GuidanceR01NS054172 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI PFAFF, SAMUEL L. · 2007 to 2011
$2.1M
Howard Hughes Medical InstituteNINDS NIH HHS R01 NS054172NINDS NIH HHS R37 NS037116NINDS NIH HHS R37NS037116
6 · The paper itself

Abstract

Motor neurons are functionally related, but represent a diverse collection of cells that show strict preferences for specific axon pathways during embryonic development. In this article, we describe the ligands and receptors that guide motor axons as they extend toward their peripheral muscle targets. Motor neurons share similar guidance molecules with many other neuronal types, thus one challenge in the field of axon guidance has been to understand how the vast complexity of brain connections can be established with a relatively small number of factors. In the context of motor guidance, we highlight some of the temporal and spatial mechanisms used to optimize the fidelity of pathfinding and increase the functional diversity of the signaling proteins.

Indexed as

AnimalsAxonsHumansLigandsModels, BiologicalMotor NeuronsMutationNeural CrestNeuronsPhenotypeSignal TransductionSpinal CordLigands

Identifiers

PMID20300210
PMCPMC2829954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.