Evidence map›Paper›PMID 20299255›Full record

ReviewSleep medicine reviews2010

Approaches to unravel the genetics of sleep.

Mikhil N Bamne, Hader Mansour, Timothy H Monk, Daniel J Buysse, Vishwajit L Nimgaonkar

Open access · greenAbstract readReview
In one paragraph

Review in Sleep medicine reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mikhil N BamneDepartment of Psychiatry, 441 Western Psychiatric Institute and Clinic, 3811 O'Hara St., University of Pittsburgh, School of Medicine, Pittsburgh, PA 15213, USA. bamnemn@upmc.edu
Hader Mansour
Timothy H Monk
Daniel J Buysse
Vishwajit L Nimgaonkar
University of Pittsburgh · US

Funding

REDUCING STRESS /SLEEP DISTURBANCES IN CAREGIVERS OF ADP01AG020677 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BUYSSE, DANIEL J. · 2003 to 2015
$17.5M
A Neurobehavioral Family Study of SchizophreniaR01MH063480 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NIMGAONKAR, VISHWAJIT LAXMIKANT · 2001 to 2018
$6.1M
Psychiatric research infrastructure for intervention and implementation in India – TEAMSD43TW009114 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Smita N Deshpande, Mary Elizabeth Hawk · 2014 to 2026
$3.2M
Training Program for Psychiatric Genetics in IndiaD43TW006167 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NIMGAONKAR, VISHWAJIT LAXMIKANT · 2002 to 2006
$1.7M
FIC NIH HHS D43 TW006167FIC NIH HHS D43 TW009114NIA NIH HHS P01 AG020677NIMH NIH HHS R01 MH063480
6 · The paper itself

Abstract

Sleep and circadian rhythms are complex and inter-connected physiological processes. Relative to the remarkable progress made in identifying the genetic basis of circadian rhythms and some specific sleep disorders, efforts to identify genetic variants associated with normal variation in sleep have progressed more slowly. Two key issues concerning the design of such studies must be addressed in order to facilitate further progress. The first concerns the sleep related traits to be targeted. The second issue is the choice of the gene-mapping method (linkage, candidate gene association or genome-wide association). This paper discusses these issues, reviews published studies of sleep phenotypes, and recommends cost-effective methods to advance knowledge of the genetic determinants of normal sleep patterns.

Indexed as

Genetic Predisposition to DiseaseChromosome MappingCircadian RhythmGene ExpressionGenetic LinkageHumansPoint MutationSleepSleep Disorders, Circadian RhythmSleep Wake Disorders

Identifiers

PMID20299255
PMCPMC2908185
OpenAlexW2132516507

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.