ArticleNeuroscience2010
Neural heterogeneities and stimulus properties affect burst coding in vivo.
Article in Neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Distributed burst firing mediates optimized cortical encoding of natural self-motion.Science advances · 2026Article
- In vivo neural activity of electrosensory pyramidal cells: Biophysical characterization and phenomenological modeling.PLoS computational biology · 2025Article
- Burst firing optimizes invariant coding of natural communication signals by electrosensory neural populations.iScience · 2025Article
- Fractional order memcapacitive neuromorphic elements reproduce and predict neuronal function.Scientific reports · 2024Article
- Descending pathways increase sensory neural response heterogeneity to facilitate decoding and behavior.iScience · 2023Article
- Article
- On the Validity of Neural Mass Models.Frontiers in computational neuroscience · 2020Article
- Novel Functions of Feedback in Electrosensory Processing.Frontiers in integrative neuroscience · 2019Article
- SK channel subtypes enable parallel optimized coding of behaviorally relevant stimulus attributes: A review.Channels (Austin, Tex.) · 2017Review
- Electrosensory neural responses to natural electro-communication stimuli are distributed along a continuum.PloS one · 2017Article
- Optimized Parallel Coding of Second-Order Stimulus Features by Heterogeneous Neural Populations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Burst Firing in the Electrosensory System of Gymnotiform Weakly Electric Fish: Mechanisms and Functional Roles.Frontiers in computational neuroscience · 2016Review
- Neural heterogeneities determine response characteristics to second-, but not first-order stimulus features.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Activation of parallel fiber feedback by spatially diffuse stimuli reduces signal and noise correlations via independent mechanisms in a cerebellum-like structure.PLoS computational biology · 2015Article
- Differential effects of excitatory and inhibitory heterogeneity on the gain and asynchronous state of sparse cortical networks.Frontiers in computational neuroscience · 2014Article
- Motion processing across multiple topographic maps in the electrosensory system.Physiological reports · 2014Article
- Neuromodulation of early electrosensory processing in gymnotiform weakly electric fish.The Journal of experimental biology · 2013Review
- Parallel coding of first- and second-order stimulus attributes by midbrain electrosensory neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Bursts and isolated spikes code for opposite movement directions in midbrain electrosensory neurons.PloS one · 2012Article
- Coding movement direction by burst firing in electrosensory neurons.Journal of neurophysiology · 2011Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Many neurons tend to fire clusters of action potentials called bursts followed by quiescence in response to sensory input. While the mechanisms that underlie burst firing are generally well understood in vitro, the functional role of these bursts in generating behavioral responses to sensory input in vivo are less clear. Pyramidal cells within the electrosensory lateral line lobe (ELL) of weakly electric fish offer an attractive model system for studying the coding properties of burst firing, because the anatomy and physiology of the electrosensory circuitry are well understood, and the burst mechanism of ELL pyramidal cells has been thoroughly characterized in vitro. We investigated the coding properties of bursts generated by these cells in vivo in response to mimics of behaviorally relevant sensory input. We found that heterogeneities within the pyramidal cell population had quantitative but not qualitative effects on burst coding for the low frequency components of broadband time varying input. Moreover, spatially localized stimuli mimicking, for example, prey tended to elicit more bursts than spatially global stimuli mimicking conspecific-related stimuli. We also found small but significant correlations between burst attributes such as the number of spikes per burst or the interspike interval during the burst and stimulus attributes such as stimulus amplitude or slope. These correlations were much weaker in magnitude than those observed in vitro. More surprisingly, our results show that correlations between burst and stimulus attributes actually decreased in magnitude when we used low frequency stimuli that are expected to promote burst firing. We propose that this discrepancy is attributable to differences between ELL pyramidal cell burst firing under in vivo and in vitro conditions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.