Evidence map›Paper›PMID 20298606›Full record

ArticleArthritis research & therapy2010

Limited educational attainment and radiographic and symptomatic knee osteoarthritis: a cross-sectional analysis using data from the Johnston County (North Carolina) Osteoarthritis Project.

Leigh F Callahan, Jack Shreffler, Bernadette C Siaton, Charles G Helmick, Britta Schoster, Todd A Schwartz, Jiu-Chiuan Chen, Jordan B Renner, Joanne M Jordan

Abstract read
In one paragraph

Article in Arthritis research & therapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Leigh F CallahanThurston Arthritis Research Center, Department of Medicine, 3300 Thurston Building, CB # 7280, University of North Carolina, Chapel Hill, NC 27599-7330, USA. leigh_callahan@med.unc.edu
Jack Shreffler
Bernadette C Siaton
Charles G Helmick
Britta Schoster
Todd A Schwartz
Jiu-Chiuan Chen
Jordan B Renner
Joanne M Jordan

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Melissa A. Troester · 2001 to 2026
$36.3M
Project 3P60AR049465 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JORDAN, JOANNE M. · 2003 to 2008
$6.0M
Women's knee motion patterns in functional activitiesP60AR030701 · NIAMS · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI CALLAHAN, LEIGH FLEMING · 1986 to 2001
$1.9M
NIAMS NIH HHS 5-P60-AR30701NIAMS NIH HHS 5-P60-AR49465NIEHS NIH HHS P30 ES010126
6 · The paper itself

Abstract

introductionApplying a cross-sectional analysis to a sample of 2,627 African-American and Caucasian adults aged > or = 45 years from the Johnston County Osteoarthritis Project, we studied the association between educational attainment and prevalence of radiographic knee osteoarthritis and symptomatic knee osteoarthritis.

methodsAge- and race-adjusted associations between education and osteoarthritis outcomes were assessed by gender-stratified logistic regression models, with additional models adjusting for body mass index, knee injury, smoking, alcohol use, and occupational factors.

resultsIn an analysis of all participants, low educational attainment (<12 years) was associated with higher prevalence of four knee osteoarthritis outcomes (unilateral and bilateral radiographic and symptomatic osteoarthritis). Women with low educational attainment had 50% higher odds of having radiographic knee osteoarthritis and 65% higher odds of symptomatic knee osteoarthritis compared with those with higher educational attainment (> or = 12 years), by using fully adjusted models. In the subset of postmenopausal women, these associations tended to be weaker but little affected by adjustment for hormone replacement therapy. Men with low educational attainment had 85% higher odds of having symptomatic knee osteoarthritis by using fully adjusted models, but the association with radiographic knee osteoarthritis was explained by age.

conclusionsAfter adjustment for known risk factors, educational attainment, as an indicator of socioeconomic status, is associated with symptomatic knee osteoarthritis in both men and women and with radiographic knee osteoarthritis in women.

Indexed as

AchievementKnee JointAgedConfounding Factors, EpidemiologicCross-Sectional StudiesEducational StatusFemaleHumansMaleMiddle AgedNorth CarolinaOsteoarthritis, KneePostmenopausePrevalenceRacial GroupsRadiography

Identifiers

PMID20298606
PMCPMC2888194

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.