Evidence map›Paper›PMID 20297778›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2010

Phospholipid complexation of general anesthetics in fluid bilayers.

Serhan Turkyilmaz, Hideyuki Mitomo, Wen-Hua Chen, Steven L Regen

Abstract read
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Serhan TurkyilmazDepartment of Chemistry, Lehigh University, Bethlehem, Pennsylvania 18015,USA.
Hideyuki Mitomo
Wen-Hua Chen
Steven L Regen

Funding

Nearest-Neighbor Recognition in Lipid BilayersR01GM056149 · NIGMS · LEHIGH UNIVERSITY · PI REGEN, STEVEN L. · 1998 to 2010
$2.6M
NIGMS NIH HHS GM56149NIGMS NIH HHS R01 GM056149
6 · The paper itself

Abstract

A nearest-neighbor recognition analysis has been performed in cholesterol-rich and cholesterol-poor liposomes derived from 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) in the presence of varying concentrations of chloroform. This analysis has yielded a fundamentally new, molecular-level view of the interaction of general anesthetics with lipid bilayers, which may be relevant to their biological action; that is, DPPC forms 1:1 complexes with CHCl(3) in both membranes in the fluid bilayer state.

Indexed as

Anesthetics, GeneralChloroformCholesterolLipid BilayersLiposomesMagnetic Resonance SpectroscopyModels, ChemicalMolecular StructurePhospholipidsAnesthetics, GeneralChloroformCholesterolLipid BilayersLiposomesPhospholipids

Identifiers

PMID20297778
PMCPMC2856843

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.