ArticleWorld journal of gastroenterology2010
Time-series gene expression profiles in AGS cells stimulated with Helicobacter pylori.
Article in World journal of gastroenterology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Glycosylation-related gene expression in HT29-MTX-E12 cells upon infection byWorld journal of gastroenterology · 2017Article
- Intragastric exposure to titanium dioxide nanoparticles induced nephrotoxicity in mice, assessed by physiological and gene expression modifications.Particle and fibre toxicology · 2013Article
- Interleukin-8 is the single most up-regulated gene in whole genome profiling of H. pylori exposed gastric epithelial cells.BMC microbiology · 2012Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo extend the knowledge of the dynamic interaction between Helicobacter pylori (H. pylori) and host mucosa.
methodsA time-series cDNA microarray was performed in order to detect the temporal gene expression profiles of human gastric epithelial adenocarcinoma cells infected with H. pylori. Six time points were selected to observe the changes in the model. A differential expression profile at each time point was obtained by comparing the microarray signal value with that of 0 h. Real-time polymerase chain reaction was subsequently performed to evaluate the data quality.
resultsWe found a diversity of gene expression patterns at different time points and identified a group of genes whose expression levels were significantly correlated with several important immune response and tumor related pathways.
conclusionEarly infection may trigger some important pathways and may impact the outcome of the infection.
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