Evidence map›Paper›PMID 20238355›Full record

SynthesisThe Cochrane database of systematic reviews2010

Glucocorticoids for the treatment of anaphylaxis.

Karen Jui Lin Choo, F Estelle R Simons, Aziz Sheikh

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.

  1. Glucocorticoids for the treatment of anaphylaxis.The Cochrane database of systematic reviews · 2012
    Pooled it
  2. Trial
  3. Fish-oil capsule ingestion: a case of recurrent anaphylaxis.Canadian family physician Medecin de famille canadien · 2012
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Karen Jui Lin ChooPrimary Care Research & Development, Centre for Population Health Sciences: GP section. The University of Edinburgh, Medical School, Doorway 3, Teviot Place, Edinburgh, UK, EH8 9AG.
F Estelle R Simons
Aziz Sheikh
University of Edinburgh · GBUniversity of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnaphylaxis is a serious hypersensitivity reaction that is rapid in onset and may result in death. Anaphylaxis guidelines recommend glucocorticoids for the treatment of people experiencing anaphylaxis.

objectivesWe sought to assess the benefits and harms of glucocorticoid treatment during episodes of anaphylaxis. SEARCH STRATEGY: We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2009, Issue 3), MEDLINE (Ovid) (1966 to September 2009), EMBASE (Ovid) (1988 to September 2009), CINAHL (EBSCOhost) (to September 2009) and The Science Citation Index Expanded (SCI-EXPANDED) (1945 to September 2009). We also searched the UK National Research Register and websites listing ongoing trials, and contacted international experts in anaphylaxis in an attempt to locate unpublished material. SELECTION CRITERIA: We included randomized and quasi-randomized controlled trials comparing glucocorticoids with any control (either placebo, adrenaline (epinephrine), an antihistamine, or any combination of these). DATA COLLECTION AND ANALYSIS: Two authors independently assessed articles for inclusion. MAIN

resultsWe found no studies that satisfied the inclusion criteria. AUTHORS'

conclusionsWe are, based on this review, unable to make any recommendations for the use of glucocorticoids in the treatment of anaphylaxis.

Indexed as

AnaphylaxisGlucocorticoidsHumansGlucocorticoids

Identifiers

PMID20238355
OpenAlexW1983902222

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.