Evidence map›Paper›PMID 20238330›Full record

SynthesisThe Cochrane database of systematic reviews2010

Continuous passive motion following total knee arthroplasty in people with arthritis.

Lisa A Harvey, Lucie Brosseau, Robert D Herbert

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02339831 (A Prospective, Randomized, Controlled, Single Center Study Evaluating the Clinical Performance of CAMOPED Following Knee Replacement), which is not on this map. Cited by 21 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02339831 nacompletednot on this map

A Prospective, Randomized, Controlled, Single Center Study Evaluating the Clinical Performance of CAMOPED Following Knee Replacement

TypeinterventionalSponsorBrigham and Women's HospitalRan2007 to 2010Enrolled110ConditionsKnee ArthroplastyArmsCAMOPED, CPM passive motion device
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Cryotherapy following total knee replacement.The Cochrane database of systematic reviews · 2023
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Passive movements for the treatment and prevention of contractures.The Cochrane database of systematic reviews · 2013
    Pooled it
  8. Efficacy of Active Exercises to Improve Range of Motion in Knee Joint After Total Knee Arthroplasty. A Randomized Controlled Trial.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Trial
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Knee and Ankle Arthroplasty in Hemophilia.Journal of clinical medicine · 2017
    Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. What Does the Cochrane Collaboration Say about Stretching Exercises?Physiotherapy Canada. Physiotherapie Canada · 2013
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Lisa A HarveyRehabilitation Studies Unit, Northern Clinical School, Sydney Medical School, The University of Sydney, PO Box 6, Ryde, NSW, Australia, 1680.
Lucie Brosseau
Robert D Herbert

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTotal knee arthroplasty is a common intervention for patients with arthritis. Post-surgical rehabilitation often includes continuous passive motion. However, it is not clear whether continuous passive motion is effective.

objectivesTo evaluate the effectiveness of continuous passive motion following total knee arthroplasty in people with arthritis. SEARCH STRATEGY: We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2009, Issue 3), MEDLINE (January 1966 to January 2009), EMBASE (January 1980 to January 2009), CINAHL (January 1982 to January 2009), AMED (January 1985 to January 2009) and PEDro (to January 2009). SELECTION CRITERIA: Randomised controlled trials in which the experimental group received continuous passive motion, and both the experimental and control groups received similar postoperative care and therapy following total knee arthoplasty in people with arthritis. DATA COLLECTION AND ANALYSIS: Two reviewers independently selected trials for inclusion. Data were then extracted and the quality of trials assessed. The primary outcomes were active knee flexion range of motion, passive knee flexion range of motion, active knee extension range of motion, passive knee extension range of motion, length of hospital stay, function and incidence of manipulation under anaesthesia. The secondary outcomes were pain, swelling and quadriceps strength. Effects were estimated as weighted mean differences or standardised mean differences with 95% confidence intervals (CI). Meta-analyses were performed using random-effects models for continuous variables. MAIN

resultsTwenty randomised controlled trials of 1335 participants met the inclusion criteria. There is high-quality evidence that continuous passive motion increases passive knee flexion range of motion (mean difference 2 degrees, 95% CI 0 to 5) and active knee flexion range of motion (mean difference 3 degrees, 95% CI 0 to 6). These effects are too small to be clinically worthwhile. There is low-quality evidence that continuous passive motion has no effect on length of hospital stay (mean difference -0.3 days; 95% CI -0.9 to 0.2) but reduces the need for manipulation under anaesthesia (relative risk 0.15; 95% CI 0.03 to 0.70). AUTHORS'

conclusionsThe effects of continuous passive motion on knee range of motion are too small to justify its use. There is weak evidence that continuous passive motion reduces the subsequent need for manipulation under anaesthesia.

Indexed as

Motion Therapy, Continuous PassiveArthroplasty, Replacement, KneeHumansOsteoarthritis, KneeRandomized Controlled Trials as TopicRange of Motion, Articular

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.