Evidence map›Paper›PMID 20237121›Full record

ArticleAnnals of the rheumatic diseases2010

Genetic variants of STAT4 associated with rheumatoid arthritis in persons of Asian and European ancestry do not replicate in African Americans.

James M Kelley, Laura B Hughes, Ashima Malik, Maria I Danila, Yuanqing Edberg, Graciela S Alarcón, Doyt L Conn, Beth L Jonas, Leigh F Callahan, Edwin A Smith and 5 more

Abstract readLetter
In one paragraph

Article in Annals of the rheumatic diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. STAT4 gene polymorphism promotes progression of rheumatoid arthritis.Journal, genetic engineering & biotechnology · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Association BetweenThe open rheumatology journal · 2018
    Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

James M Kelley
Laura B Hughes
Ashima Malik
Maria I Danila
Yuanqing Edberg
Graciela S Alarcón
Doyt L Conn
Beth L Jonas
Leigh F Callahan
Edwin A Smith
Richard D Brasington
Jeffrey C Edberg
Robert P Kimberly
Larry W Moreland
S Louis Bridges

Funding

Zonisamide in Patients with Neuropathic Pain Associated with Diabetic NeuropathyM01RR000046 · NCRR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JOY, MELANIE S · 1985 to 2008
$38.5M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Zevalin Radioimmunotherapy Using a Modified TreatmentM01RR000032 · NCRR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI RICH, ROBERT R. · 1985 to 2008
$23.6M
UAB CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCE (CCTS) UL1: BPCAUL1RR025777 · NCRR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GUAY-WOODFORD, LISA MARIE · 2008 to 2011
$22.3M
Program Project in the Genetics of SLEP01AR049084 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2002 to 2012
$12.7M
Sex Related Determinants Of Pain In FibromyalgiaP60AR048095 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ARNETT, DONNA K · 2002 to 2012
$11.7M
RA-Related Autoantibodies in Healthy FDR of RA PatientsR01AR051394 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI NORRIS, JILL M · 2005 to 2011
$3.0M
CLEAR-264002247N01AR002247 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · 2000 to 2004
$805k
POPULATION GENETICS ANALYSIS PROGRAM IMMUNITY TO VACCINES/INFECTION-266040068N01AI040068 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KASLOW, RICHARD ALAN · 2006 to 2006
–
NCATS NIH HHS UL1 TR000454NCRR NIH HHS M01 RR000032NCRR NIH HHS M01 RR000046NCRR NIH HHS UL1 RR025777NIAID NIH HHS N01 AI040068NIAMS NIH HHS N01 AR002247NIAMS NIH HHS P01 AR049084NIAMS NIH HHS P60 AR048095NIAMS NIH HHS R01 AR051394
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Polymorphism, Single NucleotideArthritis, RheumatoidAsian PeopleBlack or African AmericanGenetic Predisposition to DiseaseHumansSTAT4 Transcription FactorWhite PeopleSTAT4 protein, humanSTAT4 Transcription Factor

Identifiers

PMID20237121
PMCPMC3133745

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.