ReviewArthritis research & therapy2010
The contribution of genetic variation and infection to the pathogenesis of ANCA-associated systemic vasculitis.
Review in Arthritis research & therapy, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.
- CTLA-4 and TNF-α promoter-308 A/G polymorphisms and ANCA-associated vasculitis susceptibility: a meta-analysis.Molecular biology reports · 2012Pooled it
- Single-Cell RNA-Sequencing of Peripheral Blood Reveals Neutrophil Heterogeneity in Childhood ANCA-Associated Vasculitis.Journal of inflammation research · 2026Article
- Risk of relapse of ANCA-associated vasculitis among patients homozygous for the proteinase 3 gene Val119Ile polymorphism.RMD open · 2023Article
- The Association of Serum Anti-Lysosomal-Associated Membrane Protein-2 Antibody with Vasculitis Combined with Hypertension.International journal of hypertension · 2022Article
- Updates in ANCA-associated vasculitis.European journal of rheumatology · 2016Review
- Drug-Induced Vasculitis: New Insights and a Changing Lineup of Suspects.Current rheumatology reports · 2015Review
- The immunopathology of ANCA-associated vasculitis.Seminars in immunopathology · 2014Review
- Genetic Susceptibility to ANCA-Associated Vasculitis: State of the Art.Frontiers in immunology · 2014Review
- Antineutrophil cytoplasmic autoantibody-associated vasculitis in Chinese patients.Clinical and experimental nephrology · 2013Review
- Genetics of ANCA-associated vasculitis in Japan: a role for HLA-DRB1*09:01 haplotype.Clinical and experimental nephrology · 2013Review
- Genetically determined severity of anti-myeloperoxidase glomerulonephritis.The American journal of pathology · 2013Article
- Glomerular disease in patients with infectious processes developing antineutrophil cytoplasmic antibodies.ISRN nephrology · 2013Review
- Pathogenesis of ANCA-associated vasculitis.Current rheumatology reports · 2012Review
- Familial granulomatosis with polyangiitis: three cases of this rare disorder in one Indoasian family carrying an identical HLA DPB1 allele.BMJ case reports · 2012Article
- The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Genetically distinct subsets within ANCA-associated vasculitis.The New England journal of medicine · 2012Article
- Vasculitis: Will LAMP enlighten us about ANCA-associated vasculitis?Nature reviews. Nephrology · 2012Article
- Anti-LAMP-2 antibodies are not prevalent in patients with antineutrophil cytoplasmic autoantibody glomerulonephritis.Journal of the American Society of Nephrology : JASN · 2012Article
- Article
- Pathogenesis of anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis.Clinical and experimental immunology · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
The aetiology of anti-neutrophil cytoplasmic antibody (ANCA)-associated systemic vasculitis has not been well defined. Here we review two factors which may play a role in the pathogenesis of the disease: genetics and infection. In particular, we discuss the role of autoantibodies to LAMP-2, which may arise following infection with Gram-negative bacteria, and may contribute to the development of ANCA-associated systemic vasculitis in genetically susceptible individuals.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.